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Dr. Levenston's primary research interests relate to the function, degeneration and repair of articular cartilage and fibrocartilage, with an emphasis on understanding the complex interactions between biophysical and biochemical cues in controlling cell behavior. Current areas include the mechanisms and functional implications of cell mediated tissue degeneration in cartilage and meniscus, novel imaging techniques for nondestructive assessment of cartilage composition, and interactions between mechanical, chemical and matrix-supplied cues in controlling the development of engineered tissues.
My lab's research involves the function, degeneration and repair of musculoskeletal soft tissues, with a focus on meniscal fibrocartilage and articular cartilage. We are particularly interested in the complex interactions between biophysical and biochemical cues in controlling cell behavior, the roles of these interactions in degenerative conditions such as osteoarthritis, and development of tissue engineered 3D model systems for studying physical influences on primary and progenitor cells.