Current Research and Scholarly Interests
I develop imaging-guided therapeutic strategies to study and modulate immune responses in cancer, combining molecular imaging with targeted therapeutic development. My training is in molecular imaging, where during my doctoral work I developed and validated a PET-based approach to evaluate endocrine therapy response in advanced breast cancer.
My current research focuses on integrating immuno-oncology with experimental and translational systems, including lipid nanoparticle (LNP)-mediated mRNA delivery, in situ CAR-T cell engineering, and antibody-based therapeutics. I design and apply in vitro and in vivo models to study tumor immune markers and treatment responses, with the goal of developing integrated platforms that can both monitor and guide therapeutic interventions.
To achieve this, I use antibodies, nanoparticles, and reporter gene systems, alongside combination therapeutic strategies aimed at modulating and restoring anti-tumor immune function. This work is carried out in close collaboration with multidisciplinary teams across immunology, radiochemistry, and clinical oncology, bridging experimental research with translational and clinical applications.
