Manju Sharma

Senior Research Scientist- Basic Life, OB-GYN/Reproductive, Perinatal and Stem Cell Biology Research

All Publications

Publications (12)

All Publications (12)
Journal Articles (12)

Profiles With Related Publications

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Dr. Gregory Bean

Assistant Professor of Pathology
Clinical Focus
Anatomic Pathology, Breast Pathology, Molecular Pathology

56 Total Publications
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Linda Boxer, MD, PhD

Vice Dean of the School of Medicine and Stanley McCormick Memorial Professor
Research Interests
Regulation of expression of oncogenes in normal and malignant hematologic cells.

84 Total Publications
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Patrick O. Brown

Professor of Biochemistry, Emeritus
Research Interests
Dr. Brown, currently an emeritus professor, is CEO and founder of Impossible Foods, a company dedicated to replacing the world's most destructive technology - the use of animals to transform plant biomass into meat, fish and dairy foods - by developing a new and better way to produce the world's most delicious, nutritious and affordable meats, fish and dairy foods directly from plants. Visit impossiblefoods.com for more information.

319 Total Publications
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Anne Brunet

Michele and Timothy Barakett Endowed Professor
Research Interests
Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.

153 Total Publications
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Howard Y. Chang, MD, PhD

Virginia and D. K. Ludwig Professor of Cancer Research and Professor of Genetics
Clinical Focus
Cancer > Cutaneous (Dermatologic) Oncology, Dermatology, General Dermatology
Research Interests
Our research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.

461 Total Publications
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Raymond Chen

Lead Undergraduate Advising Director, Academic Advising Operations

8 Total Publications
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Karlene Cimprich

Professor of Chemical and Systems Biology and, by courtesy, of Biochemistry
Research Interests
Genomic instability contributes to many diseases, but it also underlies many natural processes. The Cimprich lab is focused on understanding how mammalian cells maintain genomic stability in the context of DNA replication stress and DNA damage. We are interested in the molecular mechanisms underlying the cellular response to replication stress and DNA damage as well as the links between DNA damage and replication stress to human disease.

74 Total Publications
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Gerald Crabtree

David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Research Interests
Chromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.

262 Total Publications
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Martha S. Cyert

Dr. Nancy Chang Professor
Research Interests
The Cyert lab is identifying signaling networks for calcineurin, the conserved Ca2+/calmodulin-dependent phosphatase, and target of immunosuppressants FK506 and cyclosporin A, in yeast and mammals. Cell biological investigations of target dephosphorylation reveal calcineurin’s many physiological functions. Roles for short linear peptide motifs, or SLiMs, in substrate recognition, network evolution, and regulation of calcineurin activity are being studied.

70 Total Publications
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David Feldman

Professor of Medicine (Endocrinology, Gerontology and Metabolism), Emeritus
Research Interests
Studies of the role of the vitamin D receptor in the action of 1,25-dihydroxyvitamin D, the active vitamin D hormone. Current efforts are evaluating the vitamin D receptor in breast and prostate cancer, osteoporosis and rickets.

234 Total Publications
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Amato J. Giaccia

Jack, Lulu and Sam Willson Professor, Professor of Radiation Oncology, Emeritus
Research Interests
During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically.

403 Total Publications
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Robert Hsieh

Adjunct Clinical Assistant Professor, Medicine - Oncology
Clinical Focus
Genitourinary Oncology, Prostate Cancer, Kidney (Renal) Cancer, Bladder Cancer, Testicular Cancer, Medical Oncology

13 Total Publications