Li Guan

Basic Life Research Scientist, Radiation Oncology - Radiation Therapy

All Publications

Publications (8)

All Publications (8)
Featured Publications (2)
Journal Articles (7)
Conference Proceedings (1)

Profiles With Related Publications

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Joydeep Bhadury

Instructor, Institute for Stem Cell Biology and Regenerative Medicine

15 Total Publications
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Anne Brunet

Michele and Timothy Barakett Endowed Professor
Research Interests
Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.

150 Total Publications
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Greg Charville, MD, PhD

Assistant Professor of Pathology
Clinical Focus
Soft Tissue and Bone Pathology, Gastrointestinal and Hepatopancreatobiliary Pathology, Anatomic Pathology

82 Total Publications
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Kung Chun Chiu

Postdoctoral Scholar, Pathology

21 Total Publications
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Karlene Cimprich

Professor of Chemical and Systems Biology and, by courtesy, of Biochemistry
Research Interests
Genomic instability contributes to many diseases, but it also underlies many natural processes. The Cimprich lab is focused on understanding how mammalian cells maintain genomic stability in the context of DNA replication stress and DNA damage. We are interested in the molecular mechanisms underlying the cellular response to replication stress and DNA damage as well as the links between DNA damage and replication stress to human disease.

74 Total Publications
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Michael F. Clarke, M.D.

Karel H. and Avice N. Beekhuis Professor of Cancer Biology
Research Interests
Dr. Clarke maintains a laboratory focused on two areas of research: i) the control of self-renewal of normal stem cells and diseases such as cancer and hereditary diseases; and ii) the identification and characterization of cancer stem cells. His laboratory is investigating how perturbations of stem cell regulatory machinery contributes to human disease. In particular, the laboratory is investigating epigenetic regulators of self renewal, the process by which stem cells regenerate themselves.

180 Total Publications
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Amato J. Giaccia

Jack, Lulu and Sam Willson Professor, Professor of Radiation Oncology, Emeritus
Research Interests
During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically.

403 Total Publications
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David Iberri

Clinical Assistant Professor, Medicine - Hematology
Clinical Focus
Lymphoma, Chronic Lymphocytic Leukemia, Multiple Myeloma, Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Polycythemia Vera, Essential Thrombocythemia, Myeloproliferative Disorders, Iron Deficiency Anemia, Venous Thromboembolism, Aplastic Anemia, Hematology

23 Total Publications
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Peter K. Jackson

Professor of Microbiology and Immunology (Baxter Labs) and of Pathology
Research Interests
Cell cycle and cyclin control of DNA replication .

175 Total Publications
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Stefanie S. Jeffrey, MD

John and Marva Warnock Professor, Emerita
Research Interests
Dr. Jeffrey led the multidisciplinary team from the Schools of Medicine, Engineering, and Genome Technology Center that invented the MagSweeper, an automated device that immunomagnetically captures live circulating tumor cells (CTCs) from cancer patient blood for single cell analysis or culture. Her lab also works on microfluidic technologies for tumor cell capture, characterization, and growth - with the goal of defining individual patient response to newer biologically-based cancer therapies.

159 Total Publications
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Ron Kopito

Professor of Biology
Research Interests
Our laboratory use state-of-the-art cell biological, genetic and systems-level approaches to understand how proteins are correctly synthesized, folded and assembled in the mammalian secretory pathway, how errors in this process are detected and how abnormal proteins are destroyed by the ubiquitin-proteasome system.

123 Total Publications
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Daniel Dan Liu

MD Student, expected graduation Spring 2023 Ph.D. Student in Stem Cell Biology and Regenerative Medicine, admitted Autumn 2020 MSTP Student Ph.D. Minor, Computer Science

9 Total Publications