Lauren Higdon

Instructor, Medicine - Nephrology

Academic Appointments

Instructor, Medicine - Nephrology

All Publications

Publications (19)

All Publications (19)
Journal Articles (17)
Conference Proceedings (2)

Profiles With Related Publications

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Thomas Christopher Beck

MD Student with Scholarly Concentration in Informatics & Data-Driven Medicine, expected graduation Winter 2024

7 Total Publications
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Yueh-hsiu Chien

Professor of Microbiology & Immunology
Research Interests
Contribution of T cells to immunocompetence and autoimmunity; how the immune system clears infection, avoids autoimmunity and how infection impacts on the development of immune responses.

103 Total Publications
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Gerald Crabtree

David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Research Interests
Chromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.

236 Total Publications
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Amy Fan

Ph.D. Student in Immunology, admitted Autumn 2016 REACH Postbac Research Program - Program Leader, SoM Educational Programs and Services
Research Interests
Inherited mutations in the RUNX1 gene cause a platelet disorder and increased risk of blood cancers. However, it is still unclear what actually causes progression to cancer in these patients. Using genetic editing, I am investigating how RUNX1 mutations contribute to disease.

9 Total Publications
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C. Garrison Fathman

Professor of Medicine (Immunology and Rheumatology), Emeritus
Research Interests
My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity. We have identified and characterized a gene (GRAIL) that seems to control regulatory T cell (Treg) responsiveness by inhibiting the Treg IL-2 receptor desensitization. We have characterized a gene (Deaf1) that plays a major role in peripheral tolerance in T1D. Using PBC gene expression, we have provisionally identified a signature of risk and progression in T1D.

324 Total Publications
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Alex Gitlin

Instructor, Pathology
Clinical Focus
Pathology

21 Total Publications
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Jorg Goronzy

Professor of Medicine (Immunology and Rheumatology), Emeritus

459 Total Publications
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Christian Kunder

Clinical Associate Professor, Pathology
Clinical Focus
Anatomic Pathology, Surgical Pathology, Urological Pathology, Soft Tissue Pathology, Molecular Pathology

90 Total Publications
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David B. Lewis

Professor of Pediatrics (Immunology)
Clinical Focus
Primary Immunodeficiency, Pediatrics
Research Interests
My laboratory is focused on defining cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies. We are also determinomg how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants for influenza vaccine and by using catalytically inactive Cas proteins for inducing endogenous gene expression.

169 Total Publications
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Xuanying Li

Postdoctoral Scholar, Anesthesiology, Perioperative and Pain Medicine

10 Total Publications
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Crystal Mackall

Ernest and Amelia Gallo Family Professor and Professor of Pediatrics and of Medicine
Clinical Focus
Pediatric Hematology-Oncology
Research Interests
Recent clinical studies, by us and others, have demonstrated that genetically engineered T cells can eradicate cancers resistant to all other therapies. We are identifying new targets for these therapeutics, exploring pathways of resistance to current cell therapies and creating next generation platforms to overcome therapeutic resistance. We have discovered novel insights into the biology of human T cell exhaustion and developed approaches to prevent and reverse this phenomenon.

310 Total Publications
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Jonathan Maltzman

Associate Professor of Medicine (Nephrology)

59 Total Publications