Current Research and Scholarly Interests
The foundation of the laboratory is computational science aimed at identifying biomedical phenotypes improving the mechanistic understanding, diagnosis, and treatment of neuropsychiatric disorders. The biomedical phenotypes are discovered by unbiased, machine learning-based searches across biological, neuroimaging, and neuropsychological data. This data-driven discovery currently supports the adolescent brain research of the NIH-funded National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA). The laboratory also investigates brain patterns specific to alcohol use disorder, depression, and the human immunodeficiency virus (HIV) across the adult age range, and have advanced the understanding of a variety of brain diseases including schizophrenia, Alzheimer’s disease, glioma, and aging.
