Alexandra (Sasha) Khristich

Postdoctoral Scholar, Biology

Professional Education

Master of Science, Moscow State University (2015)
Bachelor of Science, Moscow State University (2015)
Doctor of Philosophy, Tufts University (2020)
PhD, Tufts University, Biology (2020)
BS/MS, Moscow State University, Chemistry (2015)

All Publications

Profiles With Related Publications

close
Patrick O. Brown

Professor of Biochemistry, Emeritus
Research Interests
Dr. Brown, currently an emeritus professor, is CEO and founder of Impossible Foods, a company dedicated to replacing the world's most destructive technology - the use of animals to transform plant biomass into meat, fish and dairy foods - by developing a new and better way to produce the world's most delicious, nutritious and affordable meats, fish and dairy foods directly from plants. Visit impossiblefoods.com for more information.

319 Total Publications
close
Xiaoyu Chen

Postdoctoral Scholar, Psychiatry

13 Total Publications
close
Sophia Chernikova

Sr Res Scientist-Basic Ls, Neurosurgery

19 Total Publications
close
Gilbert Chu

Professor of Medicine (Oncology) and of Biochemistry
Clinical Focus
Cancer > GI Oncology, Oncology
Research Interests
After shuttering the wet lab, we have focused on: a point-of-care device to measure blood ammonia and prevent brain damage; a human protein complex that juxtaposes and joins DNA ends for repair and V(D)J recombination; and strategies for teaching students and for reducing selection bias in educational programs.

74 Total Publications
close
Karlene Cimprich

Professor of Chemical and Systems Biology and, by courtesy, of Biochemistry
Research Interests
Genomic instability contributes to many diseases, but it also underlies many natural processes. The Cimprich lab is focused on understanding how mammalian cells maintain genomic stability in the context of DNA replication stress and DNA damage. We are interested in the molecular mechanisms underlying the cellular response to replication stress and DNA damage as well as the links between DNA damage and replication stress to human disease.

74 Total Publications
close
Martha S. Cyert

Dr. Nancy Chang Professor
Research Interests
The Cyert lab is identifying signaling networks for calcineurin, the conserved Ca2+/calmodulin-dependent phosphatase, and target of immunosuppressants FK506 and cyclosporin A, in yeast and mammals. Cell biological investigations of target dephosphorylation reveal calcineurin’s many physiological functions. Roles for short linear peptide motifs, or SLiMs, in substrate recognition, network evolution, and regulation of calcineurin activity are being studied.

67 Total Publications
close
Rhiju Das

Associate Professor of Biochemistry
Research Interests
Our lab seeks an agile and predictive understanding of how nucleic acids and proteins code for information processing in living systems. We develop new computational & chemical tools to enable the precise modeling, regulation, and design of RNA and RNA/protein machines.

133 Total Publications
close
Guido A. Davidzon

Clinical Associate Professor, Radiology - Rad/Nuclear Medicine
Clinical Focus
Nuclear Medicine, Molecular Imaging, Positron Emission Tomography, Targeted Radionuclide Therapy

150 Total Publications
close
Richard Frock

Assistant Professor of Radiation Oncology (Radiation and Cancer Biology)
Research Interests
We are a functional genomics laboratory interested in elucidating mechanisms of DNA repair pathway choice and genome instability. We employ a powerful discovery platform, High-Throughput Genome-wide Translocation Sequencing (HTGTS), which maps DNA junctions at single nucleotide resolution. Our expertise overlaps many different fields including: genome editing, ionizing radiation and cancer therapeutics, V(D)J and IgH class switch recombination, and meiosis.

25 Total Publications
close
Aaron D. Gitler

Stanford Medicine Basic Science Professor
Research Interests
We investigate the mechanisms of human neurodegenerative diseases, including Alzheimer disease, Parkinson disease, and ALS. We don't limit ourselves to one model system or experimental approach. We start with yeast, perform genetic and chemical screens, and then move to other model systems (e.g. mammalian tissue culture, mouse, fly) and even work with human patient samples (tissue sections, patient-derived cells, including iPS cells) and next generation sequencing approaches.

171 Total Publications
close
Lauren Hagler

Postdoctoral Scholar, Biochemistry

1 Total Publications
close
Philip C. Hanawalt

Dr. Morris Herzstein Professor in Biology, Emeritus
Research Interests
My current interest includes two principal areas:

1. The molecular basis for diseases in which the pathway of transcription-coupled DNA repair is defective, including Cockyne syndrome (CS) and UV-sensitive syndrome (UVSS). Patients are severely sensitive to sunlight but get no cancers. See Hanawalt & Spivak, 2008, for review.

2. Transcription arrest by guanine-rich DNA sequences and non-canonical secondary structures. Transcription collisions with replication forks.

240 Total Publications