Academic Appointments

  • Clinical Instructor, Psychiatry and Behavioral Sciences

Honors & Awards

  • Young Investigator Research Forum Selected Attendee, American Academy of Sleep Medicine (2015)
  • Sheldon J. Korchin Prize for Excellence in Dissertation Research, University of California, Berkeley (2012)
  • Trainee Award for Research Excellence, Sleep Research Society (2011)
  • Student Research Award, Association of Behavioral and Cognitive Therapies (ABCT) (2009)
  • Graduate Research Fellowship, National Science Foundation (2008-2011)
  • Regent’s Intern Fellowship for Academic Excellence, University of California, Berkeley (2006-2008)
  • Graduation with Distinction, Summa Cum Laude, Stanford University (2004)
  • Psychology Grant for Undergraduate Research, Stanford University (2004)
  • Undergraduate Research Grant, Stanford University (2004)

Research & Scholarship

Current Research and Scholarly Interests

Dr. Kaplan's research interests span four (often overlapping) domains: (1) pathophysiologic aspects of insomnia and hypersomnia in mood disorders, including mechanisms, correlates, and sequelae of these sleep disturbances; (2) behavioral interventions for sleep disturbances in adults and adolescents; (3) circadian and psychosocial factors impacting sleep in adolescence; and (4) machine learning approaches to big data.


All Publications

  • Hypersomnia Subtypes, Sleep and Relapse in Bipolar Disorder Psychological Medicine Kaplan, K. A., McGlinchey, E. L., Soehner, A. M., Gershon, A., Talbot, L. S., Eidelman, P., Gruber, J., Harvey, A. 2015
  • Prevalence and clinical correlates of co-occurring insomnia and hypersomnia symptoms in depression. Journal of Affective Disorders Soehner, A. M., Kaplan, K. A., Harvey, A. G. 2014
  • Behavioral treatment of insomnia in bipolar disorder. American Journal of Psychiatry Kaplan, K. A., Harvey, A. G. 2013; 7 (170): 716-720
  • Hypersomnia in interepisode bipolar disorder: Does it have prognostic significance? Journal of Affective Disorders Kaplan, K. A., Gruber, J., Eidelman, P., Talbot, L. S., Harvey, A. G. 2011; 132 (3): 438-44
  • Hypersomnia across mood disorders: A review and synthesis Sleep Medicine Reviews Kaplan, K. A., Harvey, A. G. 2009; 13: 275-285
  • Treating Insomnia Improves Mood State, Sleep, and Functioning in Bipolar Disorder: A Pilot Randomized Controlled Trial JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY Harvey, A. G., Soehner, A. M., Kaplan, K. A., Hein, K., Lee, J., Kanady, J., Li, D., Rabe-Hesketh, S., Ketter, T. A., Neylan, T. C., Buysse, D. J. 2015; 83 (3): 564-577


    To determine if a treatment for interepisode bipolar disorder I patients with insomnia improves mood state, sleep, and functioning.Alongside psychiatric care, interepisode bipolar disorder I participants with insomnia were randomly allocated to a bipolar disorder-specific modification of cognitive behavior therapy for insomnia (CBTI-BP; n = 30) or psychoeducation (PE; n = 28) as a comparison condition. Outcomes were assessed at baseline, the end of 8 sessions of treatment, and 6 months later. This pilot was conducted to determine initial feasibility and generate effect size estimates.During the 6-month follow-up, the CBTI-BP group had fewer days in a bipolar episode relative to the PE group (3.3 days vs. 25.5 days). The CBTI-BP group also experienced a significantly lower hypomania/mania relapse rate (4.6% vs. 31.6%) and a marginally lower overall mood episode relapse rate (13.6% vs. 42.1%) compared with the PE group. Relative to PE, CBTI-BP reduced insomnia severity and led to higher rates of insomnia remission at posttreatment and marginally higher rates at 6 months. Both CBTI-BP and PE showed statistically significant improvement on selected sleep and functional impairment measures. The effects of treatment were well sustained through follow-up for most outcomes, although some decline on secondary sleep benefits was observed.CBTI-BP was associated with reduced risk of mood episode relapse and improved sleep and functioning on certain outcomes in bipolar disorder. Hence, sleep disturbance appears to be an important pathway contributing to bipolar disorder. The need to develop bipolar disorder-specific sleep diary scoring standards is highlighted.

    View details for DOI 10.1037/a0038655

    View details for Web of Science ID 000355167300013

  • Clinical case discussion: Behavioral treatment of insomnia in early recovery. Journal of Addiction Medicine (in press) Kaplan, K. A., McQuaid, J., Batki, S. L., Rosenlicht, N. 2014
  • Physical activity and sleep: Day-to-day associations among individuals with and without Bipolar Disorder Mental Health and Physical Activity (in press) McGlinchey, E. L., Gershon, A., Eidelman, P., Kaplan, K. A., Harvey, A. G. 2014
  • An evidence-based review of insomnia treatment in early recovery. Journal of Addiction Medicine (in press) Kaplan, K. A., McQuaid, J., Primrich, C., Rosenlicht, N. 2014
  • Treatment of sleep disturbance Clinical handbook of psychological disorders Kaplan, K. A., Harvey, A. G. Guilford Press. 2013; 5
  • Cognitive therapy for insomnia Encyclopedia of Sleep Soehner, A. M., Kaplan, K. A., Kanady, J., Harvey, A. G. Academic Press. 2013: 290-295
  • The nature and challenges posed by insomnia comorbid to severe psychiatric illenss. Sleep Medicine Clinics Soehner, A. M., Kaplan, K. A., Harvey, A. G. 2013; 8: 361-371
  • Restless Pillow, Ruffled Mind: Sleep and Affect Coupling in Interepisode Bipolar Disorder JOURNAL OF ABNORMAL PSYCHOLOGY Gershon, A., Thompson, W. K., Eidelman, P., McGlinchey, E. L., Kaplan, K. A., Harvey, A. G. 2012; 121 (4): 863-873


    Disturbances in sleep and affect are prominent features of bipolar disorder, even during interepisode periods. Few longitudinal studies have prospectively examined the relationship between naturally occurring sleep and affect, and no studies to date have done so during interepisode periods of bipolar disorder and using the entire set of "gold standard" sleep parameters. Participants diagnosed with bipolar I disorder who were interepisode (n = 32) and healthy controls (n = 36) completed diagnostic and symptom severity interviews, and a daily sleep and affect diary, as well as an actigraphy sleep assessment, for eight weeks (M = 54 days, ± 8 days). Mutual information analysis was used to assess the degree of statistical dependence, or coupling, between time series data of sleep and affect. As measured by actigraphy, longer sleep onset latency was coupled with higher negative affect more strongly in the bipolar group than in the control group. As measured by sleep diary, longer wakefulness after sleep onset and lower sleep efficiency were coupled with higher negative affect significantly more strongly in the bipolar group than in the control group. By contrast, there were no significant differences between groups in the degree of coupling between any measures of sleep and positive affect. Findings support the coupling of sleep disturbance and negative affect during interepisode bipolar disorder. Ongoing monitoring of sleep-affect coupling may provide an important target for intervention in bipolar disorder.

    View details for DOI 10.1037/a0028233

    View details for Web of Science ID 000311527700007

    View details for PubMedID 22845651

  • Social support and social strain in inter-episode bipolar disorder BIPOLAR DISORDERS Eidelman, P., Gershon, A., Kaplan, K., McGlinchey, E., Harvey, A. G. 2012; 14 (6): 628-640


    This study focused on social support and social strain and their cross-sectional associations with instabilities in sleep and social rhythms in inter-episode bipolar disorder (BD).Thirty-five adults diagnosed with inter-episode BD type I and 38 healthy controls completed measures of perceived social support and social strain. Group differences in support and strain were examined. Within the BD group, instabilities in sleep and social rhythms were assessed with 28 days of daily diary and actigraphy. Correlation and regression analyses were used to examine cross-sectional and prospective associations between social support, social strain, instabilities in sleep and social rhythms, and mood symptoms.The BD group reported lower social support and higher social strain than the control group. Additionally, social strain was positively correlated with manic and depressive symptoms in the BD group. Furthermore, there was a cross-sectional association between social support and more stable sleep on actigraphy in the BD group, although social support did not predict future sleep instability.These results indicate that inter-episode BD is associated with deficient social support and elevated social strain compared to controls, and that this may be due to persistent inter-episode mood symptoms. Social strain may be particularly important given its association with manic and depressive symptoms. The results also raise the possibility that sleep instability is related to poor social support in BD.

    View details for DOI 10.1111/j.1399-5618.2012.01049.x

    View details for Web of Science ID 000308286800006

    View details for PubMedID 22862999

  • Double trouble? The effects of sleep deprivation and chronotype on adolescent affect JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY Dagys, N., McGlinchey, E. L., Talbot, L. S., Kaplan, K. A., Dahl, R. E., Harvey, A. G. 2012; 53 (6): 660-667


      Two understudied risk factors that have been linked to emotional difficulties in adolescence are chronotype and sleep deprivation. This study extended past research by using an experimental design to investigate the role of sleep deprivation and chronotype on emotion in adolescents. It was hypothesized that sleep deprivation and an evening chronotype would be associated with decreased positive affect (PA), increased negative affect (NA), and lower positivity ratios.  Forty-seven healthy adolescents (aged 10-15 for girls, 11-16 for boys) participated in a sleep deprivation and a rested condition. A subsample of 24 adolescents was selected on the basis of extreme morningness or eveningness scores (based on outer quartiles of scores on the Children's Morningness-Eveningness Preferences Scale). PA and NA were measured using the Positive and Negative Affect Schedule for Children, and positivity ratios were calculated by dividing PA by NA.  Participants reported less positive affect and lower positivity ratios when sleep deprived, relative to when rested. Evening chronotypes reported less positive affect and lower positivity ratios than morning chronotypes in both rested and sleep deprivation conditions.  These findings extend previous research by suggesting that adolescents are adversely impacted by sleep deprivation, and that an evening chronotype might serve as a useful marker of emotional vulnerability. Early intervention and prevention strategies can focus on improving sleep and on using chronotherapy principles to reduce eveningness.

    View details for DOI 10.1111/j.1469-7610.2011.02502.x

    View details for Web of Science ID 000304087900007

    View details for PubMedID 22188424

  • Comparison between actigraphy, polysomnography and sleep diary in individuals with bipolar disorder Bipolar Disorders Kaplan, K. A., Talbot, L. S., Gruber, J., Harvey, A. G. 2012; 14: 870-879
  • Interventions for Sleep Disturbance in Bipolar Disorder. Sleep medicine and psychiatric illness. Harvey, A. G., Kaplan, K. A., Soehner, A. M. Lippincott Williams & Wilkins. 2012
  • The Effect of Sleep Deprivation on Vocal Expression of Emotion in Adolescents and Adults SLEEP McGlinchey, E. L., Talbot, L. S., Chang, K., Kaplan, K. A., Dahl, R. E., Harvey, A. G. 2011; 34 (9): 1233-1241


    Investigate the impact of sleep deprivation on vocal expression of emotion.Within-group repeated measures analysis involving sleep deprivation and rested conditions.Experimental laboratory setting.Fifty-five healthy participants (24 females), including 38 adolescents aged 11-15 y and 17 adults aged 30-60 y.A multimethod approach was used to examine vocal expression of emotion in interviews conducted at 22:30 and 06:30. On that night, participants slept a maximum of 2 h.Interviews were analyzed for vocal expression of emotion via computerized text analysis, human rater judgments, and computerized acoustic properties. Computerized text analysis and human rater judgments indicated decreases in positive emotion in all participants at 06:30 relative to 22:30, and adolescents displayed a significantly greater decrease in positive emotion via computerized text analysis relative to adults. Increases in negative emotion were observed among all participants using human rater judgments. Results for the computerized acoustic properties indicated decreases in pitch, bark energy (intensity) in certain high frequency bands, and vocal sharpness (reduction in high frequency bands > 1000 Hz).These findings support the importance of sleep for healthy emotional functioning in adults, and further suggest that adolescents are differentially vulnerable to the emotional consequences of sleep deprivation.

    View details for DOI 10.5665/SLEEP.1246

    View details for Web of Science ID 000294481700014

    View details for PubMedID 21886361

  • Sleep Deprivation in Adolescents and Adults: Changes in Affect EMOTION Talbot, L. S., McGlinchey, E. L., Kaplan, K. A., Dahl, R. E., Harvey, A. G. 2010; 10 (6): 831-841


    The present study investigated the impact of sleep deprivation on several aspects of affective functioning in healthy participants selected from three different developmental periods: early adolescence (ages 10-13), midadolescence (ages 13-16), and adulthood (ages 30-60). Participants completed an affective functioning battery under conditions of sleep deprivation (a maximum of 6.5 hours total sleep time on the first night followed by a maximum of 2 hours total sleep time on the second night) and rest (approximately 7-8 hours total sleep time each night for two consecutive nights). Less positive affect was observed in the sleep-deprived, compared to rested, condition. This effect held for 9 of the 12 positive affect items on the PANAS-C. Participants also reported a greater increase in anxiety during a catastrophizing task and rated the likelihood of potential catastrophes as higher when sleep deprived, relative to when rested. Early adolescents appraised their main worry as more threatening when sleep deprived, relative to when rested. These results support and extend previous research underscoring the adverse affective consequences of sleep deprivation.

    View details for DOI 10.1037/a0020138

    View details for Web of Science ID 000286125600008

    View details for PubMedID 21058849

  • Cognitive mechanisms in chronic insomnia: Processes and prospects. Sleep Medicine Clinics Kaplan, K. A., Talbot, L. S., Harvey, A. G. 2009; 4 (4): 541-548
  • Relationship between awareness of sleepiness and ability to predict sleep onset: Can drivers avoid falling asleep at the wheel? Sleep Medicine Kaplan, K. A., Itoi, A., Dement, W. C. 2007; 9 (1): 71-79
  • The impact of extra sleep on daytime alertness, vigilance, and mood. Sleep Medicine Kamdar, B. B., Kaplan, K. A., Kezirian, E. J., Dement, W. C. 2004; 5: 441-448