Joseph C. Wu, MD, PhD

Director, Stanford Cardiovascular Institute, Simon H. Stertzer, MD, Professor and Professor of Radiology

Bio

Dr. Wu is a board-certified cardiologist. He is the director of the Stanford Cardiovascular Institute and the Simon H. Stertzer, MD, Professor of Medicine and Radiology at Stanford University School of Medicine.

The American Heart Association appointed Dr. Wu as its president for fiscal year 2023-2024.

His clinical interests include adult congenital heart disease and cardiovascular imaging. He strives to help each patient achieve the best possible heart health and quality of life.

To advance heart care, Dr. Wu conducts extensive research, focusing on clinical genomics, stem cells, and drug development. The goals of his research are to enhance our understanding of cardiovascular diseases, accelerate the discovery of new drug treatments, and ensure that every cardiovascular patient will benefit from the best of personalized precision medicine being developed at Stanford Medicine.

Dr. Wu has published more than 550 manuscripts with H-index of 124, and is one of the world’s most highly cited scholars in the field of cardiovascular medicine, stem cells, genomics, and precision medicine. His work has appeared in peer-reviewed journals including Nature, Cell, Science, Nature Medicine, Science Translational Medicine, Cell Stem Cell, PNAS, Circulation, Journal of the American College of Cardiology, European Heart Journal, and many more. Dr. Wu also educates the heart specialists of the future. More than 45 of his trainees are now principal investigators of clinical or research studies in major academic centers both in the US and internationally.

He has earned numerous honors, including the Distinguished Scientist Award from the American Heart Association and the Director’s New Innovator Award and Transformative Award from the National Institutes of Health. He also received the Presidential Early Career Award for Scientists and Engineers (PECASE) from the White House Office of Technology.

Dr. Wu is an elected member of the National Academy of Medicine (NAM), National Academy of Inventors (NAI), American Association for the Advancement of Science (AAAS), American Society for Clinical Investigation (ASCI), Association of American Physicians (AAP), Academia Sinica (Taiwan), Association of University Cardiologists (AUC), and American Institute for Medical and Biological Engineering (AIMBE). He is an honorary lifetime member of the Society of Toxicology (SOT).

Clinical Focus

Congenital Heart Disease (Adult)
Cardiovascular Disease
Cardiovascular Imaging

Academic Appointments

Professor, Medicine - Cardiovascular Medicine
Professor, Radiology
Member, Bio-X
Director, Cardiovascular Institute
Member, Maternal & Child Health Research Institute (MCHRI)
Faculty Fellow, Sarafan ChEM-H
Member, Stanford Cancer Institute
Member, Wu Tsai Neurosciences Institute

Administrative Appointments

Director, Stanford Cardiovascular Institute (2013 - Present)

Honors & Awards

President-Elect, American Heart Association (2022)
Member, National Academy of Inventors (2022)
Academician, Academia Sinica (2022)
Board of Directors, Keystone Symposia (2022)
Honorary Lifetime Member, Society of Toxicology (2021)
Member, National Academy of Medicine (2019)
Member, American Association for the Advancement of Science (2019)
Highly Cited Researcher (Top 1% in Web of Science), Clarivate Analytics (2018-2021)
Distinguished Scientist Award, American Heart Association (2018)
Member, American Institute for Medical and Biological Engineering (2018)
Merit Award, American Heart Association (2017)
Member, Association of American Physicians (AAP) (2015)
Joseph A. Vita Award, American Heart Association (2015)
Council Member, American Society Clinical Investigation (2014-2017)
Distinguished Investigator Award, Academy of Radiology Research (2014)
Established Investigator Award, American Heart Association (2013)
Member, Association of University Cardiologists (AUC) (2013)
Member, American Society Clinical Investigation (ASCI) (2012)
Presidential Early Career Award for Scientists and Engineers (PECASE), White House Office of Technology (2010)
NIH Roadmap Transformative Award, National Institutes of Health (2009-2014)
NIH Director's New Innovator Award, National Institutes of Health (2008-2013)

Boards, Advisory Committees, Professional Organizations

Editorial Board, StemJournal (2018 - Present)
Senior Advising Editor, Cardiovascular Research (2018 - Present)
Advisory Board, Nature Reviews Cardiology (2017 - Present)
Chair, AHA Research Committee (2017 - Present)
Member, AHA National Board of Directors (2017 - Present)
Member, Cellular, Tissue, and Gene Therapies Advisory Committee (FDA) (2017 - Present)
Editorial Board, International Journal of Cardiology (2016 - Present)
Associate Editor, Circulation Research (2015 - Present)
Editorial Board, Scientific Report (2015 - Present)
Editorial Board, Current Cardiovascular Imaging Reports (2015 - Present)
Editorial Board, Current Protocols in Stem Cell Biology (2015 - 2017)
Editorial Board, Cytotherapy (2014 - Present)
Scientific Advisory Board Member, Keystone Symposia (2014 - Present)
Editorial Board, Physiological Genomics (2013 - 2016)
Editorial Board, Journal Clinical Investigation (2012 - Present)
Editorial Board, Molecular Therapy (2011 - Present)
Editorial Board, Stem Cell Research (2011 - Present)
Editorial Board, Journal Geriatric Cardiology (2011 - 2015)
Editorial Board, Human Gene Therapy (2009 - Present)
Editorial Board, Journal Nuclear Cardiology (2009 - 2018)
Editorial Board, Circulation: Cardiovascular Imaging (2008 - Present)
Editorial Board, JACC: Cardiovascular Imaging (2008 - 2018)

Professional Education

Medical Education: Yale School Of Medicine (1997) CT
Fellowship, UCLA Medical Center, Cardiovascular Medicine (2004)
PhD, UCLA, Molecular & Medical Pharmacology (2004)
MD, Yale University School of Medicine, Medicine (1997)
BS, UCLA, Biology (1993)

Contact

Academic joewu@stanford.edu Tel: (650) 736-2246 Fax: (650) 736-0234

Administrative Contact Francesca Tongo Cardiovascular Institute ftongco@stanford.edu Tel: (650) 736-9206

Clinical Cardiovascular Medicine 300 Pasteur Dr Rm A260 MC 5319 Stanford CA 94305 Tel: (650) 723-6145 Fax: (650) 723-8392
Clinical 265 Campus Dr G1120B MC 5454 Stanford CA 94305 Tel: (650) 736-2246 Fax: (650) 736-0234

Current Research and Scholarly Interests

His lab works on cardiovascular genomics and induced pluripotent stem cells (iPSCs). The main goals are to (i) understand basic disease mechanisms, (ii) accelerate drug discovery and screening, (iii) develop “clinical trial in a dish” concept, and (iv) implement precision medicine for patients.

Clinical Trials

NBS10 (Also Known as AMR-001) Versus Placebo Post ST Segment Elevation Myocardial Infarction Recruiting
More
This study will assess the safety and efficacy of intracoronary artery administered autologous bone marrow derived stem cells in subjects post ST segment elevation myocardial infarction (STEMI). This will be assessed by evaluating and comparing the autologous stem cell treatment group to the control group in terms of the occurrence of AE's, SAE's and Major Adverse Cardiac Events (MACE), by the change in myocardial perfusion (RTSS) measured quantitatively by gated single photon emission computed tomography myocardial perfusion imaging (gated SPECT MPI), and other secondary endpoints such as LVEF measured by cardiac MRI in addition to other endpoints.
Lead Sponsor
Stanford Investigators
- Joseph C. Wu, MD, PhD
View full details

2023-24 Courses

Independent Studies
- Bioengineering Problems and Experimental Investigation
  BIOE 191 (Win, Spr)
- Directed Investigation
  BIOE 392 (Aut, Win, Spr)
- Directed Reading in Immunology
  IMMUNOL 299 (Aut, Win, Spr, Sum)
- Directed Reading in Medicine
  MED 299 (Aut, Win, Spr, Sum)
- Directed Reading in Radiology
  RAD 299 (Aut, Sum)
- Directed Reading in Stem Cell Biology and Regenerative Medicine
  STEMREM 299 (Aut, Win, Spr, Sum)
- Directed Study
  BIOE 391 (Aut, Win, Spr)
- Early Clinical Experience in Immunology
  IMMUNOL 280 (Aut, Win, Spr, Sum)
- Early Clinical Experience in Medicine
  MED 280 (Aut, Win, Spr, Sum)
- Early Clinical Experience in Radiology
  RAD 280 (Aut, Sum)
- Graduate Research
  IMMUNOL 399 (Aut, Win, Spr, Sum)
- Graduate Research
  MED 399 (Aut, Win, Spr, Sum)
- Graduate Research
  RAD 399 (Aut, Sum)
- Graduate Research
  STEMREM 399 (Aut, Win, Spr, Sum)
- Medical Scholars Research
  MED 370 (Aut, Win, Spr, Sum)
- Medical Scholars Research
  RAD 370 (Aut, Sum)
- Medical Scholars Research
  STEMREM 370 (Aut, Win, Spr, Sum)
- Out-of-Department Advanced Research Laboratory in Bioengineering
  BIOE 191X (Aut, Win, Spr)
- Out-of-Department Graduate Research
  BIO 300X (Spr)
- Out-of-Department Undergraduate Research
  BIO 199X (Aut, Win, Spr)
- Teaching in Immunology
  IMMUNOL 290 (Aut, Win, Spr, Sum)
- Undergraduate Research
  IMMUNOL 199 (Aut, Win, Spr, Sum)
- Undergraduate Research
  MED 199 (Aut, Win, Spr, Sum)
- Undergraduate Research
  RAD 199 (Aut, Sum)
- Undergraduate Research
  STEMREM 199 (Aut, Win, Spr, Sum)

Stanford Advisees

Med Scholar Project Advisor
Brian Yu
Doctoral Dissertation Reader (AC)
Ching-Ting Tsai
Postdoctoral Faculty Sponsor
Bernardo Bonilauri, Xu Cao, Arianne Caudal, Sangkyun Cho, Yuanyuan Dai, Jingshan Gao, James Jahng, Nerea Jimenez Tellez, Cody Juguilon, Ana Kojic, Xiaohui Kong, Lichao Liu, Wenqiang Liu, Yu Liu, Amit Manhas, McKay Mullen, Shane R. Zhao, Lu Ren, Francesca Vacante, Ravichandra Venkateshappa, Carlos Vera, Mingqiang Wang, Xuekun Wu, Zehra Yildirim, Wenshu Zeng, Mao Zhang, Wenjuan Zhu, Pete Zushin
Doctoral Dissertation Advisor (AC)
Angela Zhang

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