Current Research and Scholarly Interests
We are a highly interdisciplinary research team, joined in our desire to better understand microbial life. To elucidate how bacterial cells accumulate biomass and grow, we work with the model organism Escherichia coli. Our approaches tightly combine quantitative experimentation with mathematical modeling to consider the coordination of major physiological processes across scales; from metabolism and protein synthesis, via cell-size control, to swimming. We further focus on gut bacteria and their interactions with the human host. Our analyses include considerations of intestinal physiology and diet patterns on the host side, as well as metabolism, growth-physiology, and ecology on the bacterial side.