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Internal, family, emergency medicine.
Alam Sehat Lestari (ASRI)/Health in Harmony
Adults and Children
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Hypnosis for perioperative symptom management in elective orthopedic surgery.
COMT Activity and Hypnotizability
Hypnosis is an effective pain management tool for surgery that can reduce opioid use up to 40%. COMT single nucleotide polymorphisms (SNPs) can predict pain sensitivity and opioid use perioperatively, and may also be associated with hypnotizability or response to hypnotic analgesia. Analyzing COMT haplotypes from DNA extracted from saliva or blood using a giant magnetoresistive (GMR) nanotechnology platform may be faster, less expensive, and at least as accurate as pyrosequencing. This study aims to validate a multi-SNP point-of-care (POC) GMR assay for the rapid genotyping of SNPs predictive of COMT activity, and test the feasibility of using COMT activity as a biomarker for hypnotizability and/or response to hypnotic analgesia.
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Validating the New Remote Hypnotic Induction Profile (rHIP) Not Recruiting
The purpose of the study is to determine if hypnotizability can be reliably tested over the phone, without having to see or touch a patient. The scores from a new test for hypnotizability by phone will be compared to the scores from a standard in-person test, to make sure the results are similar.
Stanford is currently not accepting patients for this trial. For more information, please contact Jessie Kittle, MD, 650-723-4000.
Hypnosis for Symptom Management in Elective Orthopedic Surgery Not Recruiting
The purpose of the study is to determine if teaching self-hypnosis techniques to patients prior to knee replacement surgery will decrease their pain medication requirements, pain medication side-effects, length of stay in the hospital, readmission rates, pain, anxiety, physical function, satisfaction scores, and cost of admission.
Stanford is currently not accepting patients for this trial. For more information, please contact Jessie Kittle, MD, 831-840-0599.
