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R. Jeremy Nichols
Sr Res Scientist, Pathology - Montine Lab
Education & Certifications
Post-doc, MRC Protein Phosphorylation Unit, Signal Transduction (2010)
PhD, Medical College of Wisconsin, kinases & molecular genetics (2006)
BS, Austin Peay State University, Biology (2000)
Senior Research Scientist
10 Results / Page
Profiles With Related Publications
Michele and Timothy Barakett Endowed Professor
Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.
Professor of Molecular and Cellular Physiology, of Neurology, of Photon Science and, by courtesy, of Structural Biology
One of Axel Brunger's major goals is to decipher the molecular mechanisms of synaptic neurotransmitter release by conducting imaging and single-molecule/particle reconstitution experiments, combined with near-atomic resolution structural studies of the synaptic vesicle fusion machinery.
Professor of Chemical and Systems Biology and, by courtesy, of Biochemistry
Genomic instability contributes to many diseases, but it also underlies many natural processes. The Cimprich lab is focused on understanding how mammalian cells maintain genomic stability in the context of DNA replication stress and DNA damage. We are interested in the molecular mechanisms underlying the cellular response to replication stress and DNA damage as well as the links between DNA damage and replication stress to human disease.
David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Chromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.
Younger Family Professor and Professor of Structural Biology
Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology. We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.
Associate Professor of Biochemistry
Scientific breakthroughs often come on the heels of technological advances; advances that expose hidden truths of nature, and provide tools for engineering the world around us. Examples include the telescope (heliocentrism), the Michelson interferometer (relativity) and recombinant DNA (molecular evolution). Our lab explores innovative experimental approaches to problems in molecular biochemistry, focusing on technologies with the potential for broad impact.
Peter K. Jackson
Professor of Microbiology and Immunology (Baxter Labs) and of Pathology
Cell cycle and cyclin control of DNA replication .
Professor of Structural Biology
The Jardetzky laboratory is studying the structures and mechanisms of macromolecular complexes important in viral pathogenesis, allergic hypersensitivities and the regulation of cellular growth and differentiation, with an interest in uncovering novel conceptual approaches to intervening in disease processes. Ongoing research projects include studies of paramyxovirus and herpesvirus entry mechanisms, IgE-receptor structure and function and TGF-beta ligand signaling pathways.
Professor of Biology
Our laboratory use state-of-the-art cell biological, genetic and systems-level approaches to understand how proteins are correctly synthesized, folded and assembled in the mammalian secretory pathway, how errors in this process are detected and how abnormal proteins are destroyed by the ubiquitin-proteasome system.
Robert W. and Vivian K. Cahill Professor of Cancer Research and Professor, by courtesy, of Computer Science
Stanford Professor of Biophysics and Computational Biology, Cambridge PhD and DSc, 2013 Chemistry Nobel Laureate (complex systems), FRS & US National Academy member, I code well for my age.
Sr Res Engineer
Rachford and Carlota Harris Professor
Dr. Nolan's group uses high throughput single cell analysis technology cellular biochemistry to study autoimmunity, cancer, virology (influenza & Ebola), as well as understanding normal immune system function. Using advanced flow cytometric techniques such as Mass Cytometry, MIBI (ion beam imaging), CODEX and computational biology approaches, we focus on understanding disease processes at the single cell level. We have a strong interest in cancer immunotherapy and pathogen-host interactions.
Publication Topics For This Person
Aged, 80 and over
Amino Acid Sequence
Green Fluorescent Proteins
Intracellular Signaling Peptides and Proteins
Molecular Sequence Data
Protein Serine-Threonine Kinases
Swiss 3T3 Cells