Latest information on COVID-19
Support teaching, research, and patient care.
Dr. McNab is an MRI Physicist focused on the development of magnetic resonance imaging (MRI) contrast mechanisms and acquisition strategies that yield new and/or improved images of the in vivo human brain. Over the past decade, she has developed numerous MRI acquisition methods, with her primary contributions being in the field of diffusion MRI. Dr. McNab has extensive experience with the most cutting-edge MRI technology, including the world's strongest human-MRI gradients (300 mT/m), highly-parallelized phased-array RF coils (64-channels) and ultra-high magnetic field (7T).
My research is focused on developing magnetic resonance imaging (MRI) methods that probe brain tissue microstructure. This requires new MRI contrast mechanisms, strategic encoding and reconstruction schemes, physiological monitoring, brain tissue modeling and validation. Applications of these methods include neuronavigation, neurosurgical planning and the development of improved biomarkers for brain development, degeneration, disease and injury. Active projects include: - development of q-space trajectory imaging methods for probing tissue microstructure - development of diffusion MRI methods for mapping cortical fiber patterns - comparisons of MRI with CLARITY 3D histology - development of a mixed-reality neuronavigation system for TMS - leveraging 7T MRI for predicting healthy versus pathological aging - developing diffusion tractography-based neurosurgical targeting methods