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Dr. Bruno is a translational researcher at the interface of developmental cognitive neuropsychology and neurobiology. An overarching goal of her work is to understand developmental windows of vulnerability—periods of risk for falling off the trajectory of typical brain development. Her research utilizes genetics, brain imaging, and deep behavioral phenotyping to bridge computational science with clinical knowledge, translating cutting-edge science to solve problems of great clinical need. She is currently a PI on a career development award (K01) from the National Institute on Aging. This project explores the intersection between Down syndrome and aging, with ultimate goals of informing the development of treatments for persons with Down syndrome and better understanding Alzheimer’s disease in the general population.