Bio

Honors & Awards


  • Intramural Research Training Award, National Institutes of Health (2008-2009)

Education & Certifications


  • Bachelor of Science, Stanford University, BIOL-BSH (2008)
  • Bachelor of Science, Stanford University, MUSIC-MIN (2008)

Clerkships


  • 2013 Spring - NENS 301A General Neurology Core Clerkship
  • 2013 Summer - MED 312C Advanced Medicine Clerkship
  • 2013 Summer - MED 313A Ambulatory Medicine
  • 2013 Summer - OPHT 398A Elective in Ophthalmology
  • 2012 Spring - PSYC 300A Basic Core Psychiatry Clerkship
  • 2012 Summer - OPHT 302A Bay Area Ophthalmology Course: Fundamentals in Clinical and Visual Science
  • 2012 Summer - SURG 313A Emergency Medicine Clerkship
  • 2012 Winter - ANES 306A Critical Care Core Clerkship - Adult
  • 2012 Winter - OBGYN 300A Basic Gynecology and Obstetrics Clerkship
  • 2012 Winter - OPHT 300E Ophthalmology Clerkship
  • 2011 Autumn - MED 300A General Medicine Core Clerkship
  • 2011 Autumn - SURG 300A General Surgery Clerkship
  • 2011 Summer - MED 300A General Medicine Core Clerkship
  • 2011 Summer - PEDS 300A Child Health Clerkship

Stanford Advisors


Research & Scholarship

Current Research and Scholarly Interests


Current work: Developing MRI techniques for imaging the visual pathway and nerve degeneration during ischemia

Previous work: Developing flow cytometry methods for purifying cancer stem cells in acute myelogenous leukemia

Current Clinical Interests


  • Stem Cell Transplantation
  • Ophthalmology
  • Optic Nerve Diseases
  • Imaging, Brain
  • Tomography, Optical Coherence

Publications

Journal Articles


  • In vitro and in vivo antimicrobial activity of granulysin-derived peptides against Vibrio cholerae JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Galvao da Silva, A. P., Unks, D., Lyu, S., Ma, J., Zbozien-Pacamaj, R., Chen, X., Krensky, A. M., Clayberger, C. 2008; 61 (5): 1103-1109

    Abstract

    To determine the antibacterial activity of synthetic peptides derived from the cationic antimicrobial peptide granulysin against Vibrio cholerae.The antibacterial activity of granulysin-derived peptides was assessed in vitro by microtitre and cfu assays. Toxicity against human peripheral blood mononuclear cells (PBMCs) was measured by propidium iodide uptake and haemolysis by measuring the levels of haemoglobin released after incubation of red blood cells (RBCs) with granulysin peptides. The ability of granulysin peptides to control bacterial growth in vivo was tested by the treatment of suckling mice infected with V. cholerae with granulysin peptides, administered by gavage 1 h after infection and determining the number of bacteria in the small and large intestines 24 h after infection.All peptides tested inhibited V. cholerae growth in vitro, and they were more effective against stationary phase cells. Two peptides, G12.21 and G14.15, effectively controlled bacterial growth in vivo. The peptides did not lyse RBCs and, with the exception of two peptides, exhibited very little toxicity against human PBMCs.These results suggest that granulysin-derived peptides are candidates for the development of new agents for the treatment of V. cholerae infection.

    View details for DOI 10.1093/jac/dkn058

    View details for Web of Science ID 000254955300024

    View details for PubMedID 18310138

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