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My initial research activities have focused on three areas: antiretroviral and novel therapeutic treatments of HIV infection, understanding elements of HIV pathogenesis associated with acute HIV infection and post exposure prevention. My most recent scholarly activities concentrate on working as a team to capitalize on the data stored in electronic medical records, HIV disease modeling and using electronic medical records for outcome research and developing a mentorship program for doctoral, post-doctoral scholars and early career faculty dedicated to translational and clinical research. I have experience as the national chair for an NIAID sponsored AIDS Clinical Trials Group study and I have conducted Phase 1 through Phase 3 studies. My scholarship has been supported by funding from the NIH for 24 years through a variety of mechanisms including, as the principal investigator of R01, R18, R24, R35 and K24 grants and co-investigator for R01, R18, R24 and R33 awards. Three foundations have supported my scholarly activities: the California Healthcare Foundation, the Blue Shield Foundation and the Commonwealth Foundation and I have received three career awards, one from the American Cancer Society and two K24 awards from the NIH (NIMH and NCRR).