School of Medicine
Showing 1-41 of 41 Results
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Gill Bejerano
Professor of Developmental Biology, of Computer Science, of Pediatrics (Genetics) and of Biomedical Data Science
Current Research and Scholarly Interests Dr. Bejerano, co-discoverer of ultraconserved elements, studies the Human Genome. His research focuses on genome sequence and function in both humans and related primate, mammalian and vertebrate species. He is deeply interested in mapping both coding and non-coding genome sequence variation to phenotype differences, and in extracting specific genetic insights from high throughput sequencing measurements, in the contexts of development and developmental abnormalities.
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Jon Bernstein
Professor of Pediatrics (Genetics) at the Lucile Salter Packard Children's Hospital and, by courtesy, of Genetics
Current Research and Scholarly Interests My research is focused on the diagnosis, discovery and delineation of rare genetic conditions with a focus of neurodevelopmental disorders. This work includes the application of novel computational methods and multi-omics profiling (whole genome sequencing, RNA sequencing, metabolomics). I additionally participate in an interdisciplinary project to develop induced pluripotent stem cell (iPSC) models of genetic neurodevelopmental disorders..
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Tina Cowan
Professor of Pathology (Clinical) and, by courtesy, of Pediatrics (Genetics) at the Stanford University Medical Center
Current Research and Scholarly Interests screening and diagnosis of patients with inborn errors of metabolism, including newborn screening, development of new testing methods and genotype/phenotype correlations.
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John W. Day, MD, PhD
Professor of Neurology, of Pediatrics (Genetics) and, by courtesy, of Pathology at the Stanford University Medical Center
Current Research and Scholarly Interests Our Neuromuscular Division coordinates a comprehensive effort to conquer peripheral nerve and muscle disorders, including the muscular dystrophies, motor neuron disorders, neuromuscular junction abnormalities, and peripheral neuropathies. With patients and families foremost in mind, we have had success defining and combating these diseases, with research focused on identifying genetic causes, developing novel treatment, and maximizing patient function by optimizing current management.
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Gregory Enns
Professor of Pediatrics (Genetics) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests mitochondrial genomics, lysosomal disorders, tandem-mass spectrometry newborn screening, and inborn errors of metabolism presentations and natural history
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Uta Francke
Professor of Genetics and of Pediatrics, Emerita
Current Research and Scholarly Interests Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models. Integration of genomic information into medical care.
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Natalia Gomez-Ospina
Assistant Professor of Pediatrics (Genetics) and of Pediatrics (Stem Cell Transplantation)
Current Research and Scholarly Interests Dr. Gomez-Ospina is a physician scientist and medical geneticist with a strong interest in the diagnosis and management of genetic diseases.
1) Lysosomal storage diseases:
Her research program is on developing better therapies for a large class of neurodegenerative diseases in children known as lysosomal storage disorders. Her current focus is on developing genome editing of hematopoietic stem cells as a therapeutic approach for these diseases beginning with Mucopolysaccharidosis type 1 and Gaucher disease. She established a genetic approach where therapeutic proteins can be targeted to a single well-characterized place in the genome known as a safe harbor. This approach constitutes a flexible, ?one size fits all? approach that is independent of specific genes and mutations. This strategy, in which the hematopoietic system is commandeered to express and deliver therapeutic proteins to the brain can potentially change the current approaches to treating childhood neurodegenerative diseases and pave the way for alternative therapies for adult neurodegenerative disorders such as Alzheimer?s and Parkinson?s disease
2) Point of care ammonia testing
She also works in collaboration with other researchers at Stanford to develop point-of-care testing for serum ammonia levels. Such device will greatly improve the quality of life of children and families with metabolic disorders with hyperammonemia.
3) Gene discovery
Dr Gomez-Ospina lead a multi-institutional collaboration resulting in the discovery of a novel genetic cause of neonatal and infantile cholestatic liver disease. She collaborated in the description of two novel neurologic syndromes caused by mutations in DYRK1 and CHD4.
For more information go to our website:
https://www.gomezospina.com/ -
Louanne Hudgins
Professor of Pediatrics (Genetics) at the Lucile Salter Packard Children's Hospital, Emerita
Current Research and Scholarly Interests I am interested in prenatal genetic screening and diagnosis.
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Akash Kumar
Adjunct Clinical Instructor, Pediatrics - Medical Genetics
Current Research and Scholarly Interests Akash is passionate about taking advances in genomics and applying them for patient care. After training in Chemical and Bioengineering at the University of Minnesota and Stanford University he started the Medical Scientist Training Program (MSTP) at the University of Washington and obtained a PhD in Genome Sciences. With his thesis advisor, Jay Shendure, Akash used next generation sequencing technologies to characterize the development and evolution of prostate cancer and glioblastoma. He also designed and implemented new methods using next-generation sequencing with applications for cancer genetics and prenatal genetic testing. He has published six first-author publications in journals including Nature Medicine, PNAS and Genome Medicine and is a co-inventor on one licensed patent. As a medical geneticist, Akash believes that the best approach to improve outcomes for children with complex congenital medical conditions stems from earlier diagnosis and intervention. To that effect, his current research goals are 1) to develop new genomic methods that identify children at risk for complex congenital diseases earlier, 2) to understand the molecular mechanisms of neurodevelopmental disease in children that may serve as potential avenues for treatment and 3) to improve access and implementation of genomics more broadly in the clinic.
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Tia Moscarello, MS, LCGC
Clinical Instructor (Affiliated) [Shc], Pediatrics - Genetics
Bio Licensed and certified genetic counselor with a specialization in inherited cardiovascular disease. Primary genetic counselor for the first on-call cardiovascular genetic counseling service. Clinical instructor for the Stanford University MS in Human Genetics and Genetic Counseling Program.
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Mitchel Pariani
Clinical Assistant Professor (Affiliated) [Shc], Pediatrics - Genetics
Bio Mitchel earned his Master?s degree in genetic counseling from California State University, Northridge in 2007. At Cedars-Sinai Medical Center Mitchel served as genetic counselor and coordinator for David Rimoin, MD, PhD?s connective tissue disorders clinic and later established the cardiovascular genetics program at CSMC. At CSMC he also created the CSMC Summer Genetic Counseling Rotation Program that hosted students from genetic counseling programs around the United States. In 2014 he joined the new Stanford Center for Inherited Cardiovascular Disease to start a familial hypercholesterolemia clinic and provide genetic counseling for patients with cardiomyopathies. As the center expanded, Mitchel joined the Stanford Marfan Center as a genetic counselor and serves as program coordinator. He is the primary instructor for Stanford?s Cardiovascular Genetics course and serves as a clinical supervisor and mentor for students and volunteers.
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maura ruzhnikov
Clinical Assistant Professor, Neurology & Neurological Sciences
Bio Child neurologist and medical geneticist focusing on the diagnosis and management of rare neurologic disorders. Specific interests are in genetic epilepsy syndromes, childhood neurodegenerative and neurometabolic diseases and undiagnosed suspected genetic conditions.
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David Stevenson
Professor of Pediatrics (Genetics) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests My research focuses on disorders of the RAS/MAPK pathway (eg. NF1, Noonan, CFC, and Costello syndrome). I am working on understanding the impact of RAS signaling on the musculoskeletal system. I use genomic approaches to identify somatic events and modifiers in the RASopathies. I am also involved in identifying outcome measures for use in clinical trials for the associated orthopedic manifestations. Other areas of research involve vascular anomalies, Prader-Willi syndrome, and hypophosphatasia.
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Hannes Vogel MD
Professor of Pathology and of Pediatrics (Pediatric Genetics) and, by courtesy, of Neurosurgery and of Comparative Medicine at the Stanford University Medical Center
Current Research and Scholarly Interests My research interests include nerve and muscle pathology, mitochondrial diseases, pediatric neurooncology, and transgenic mouse pathology.
