School of Medicine
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David B. Lewis
Professor of Pediatrics (Immunology) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests My laboratory is focused on defining cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies. We are also determinomg how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants for influenza vaccine and by using catalytically inactive Cas proteins for inducing endogenous gene expression.