School of Medicine
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Professor of Genetics, Emerita
Current Research and Scholarly Interests My lab is developing innovative gene and stem cell therapies for genetic diseases, with a focus on gene therapy and regenerative medicine.
We have created novel methods for inserting therapeutic genes into the chromosomes at specific places by using homologous recombination and recombinase enzymes.
We are working on 3 forms of muscular dystrophy.
We created induced pluripotent stem cells from patient fibroblasts, added therapeutic genes, differentiated, and engrafted the cells.
Associate Professor of Bioengineering
Bio David B. Camarillo is Assistant Professor of Bioengineering, (by courtesy) Mechanical Engineering and Neurosurgery at Stanford University. Dr. Camarillo holds a B.S.E in Mechanical and Aerospace Engineering from Princeton University, a Ph.D. in Mechanical Engineering from Stanford University and completed postdoctoral fellowships in Biophysics at the UCSF and Biodesign Innovation at Stanford. Dr. Camarillo worked in the surgical robotics industry at Intuitive Surgical and Hansen Medical, before launching his laboratory at Stanford in 2012. His current research focuses on precision human measurement for multiple clinical and physiological areas including the brain, heart, lungs, and reproductive system. Dr. Camarillo has been awarded the Hellman Fellowship, the Office of Naval Research Young Investigator Program award, among other honors including multiple best paper awards in brain injury and robotic surgery. His research has been funded by the NIH, NSF, DoD, as well as corporations and private philanthropy. His lab?s research has been featured on NPR, the New York Times, The Washington Post, Science News, ESPN, and TED.com as well as other media outlets aimed at education of the public.
Associate Professor of Microbiology and Immunology
Current Research and Scholarly Interests Our research focuses on the identification of host genes that play critical roles in the pathogenesis of infectious agents including viruses. We use haploid genetic screens in human cells as an efficient approach to perform loss-of-function studies. Besides obtaining fundamental insights on how viruses hijack cellular processes and on host defense mechanisms, it may also facilitate the development of new therapeutic strategies.
Clinical Professor, Pediatrics - Adolescent Medicine
Current Research and Scholarly Interests Female athlete triad; adolescents and eating disorders; athletes and supplement use; effects of sports involvement on adolescent self-esteem.
Professor (Research) of Pediatrics (Neonatology), of Obstetrics & Gynecology (Maternal Fetal Medicine) and, by courtesy, of Health Research and Policy (Epidemiology)
Current Research and Scholarly Interests Dr. Carmichael is a perinatal and nutritional epidemiologist and Professor of Pediatrics at the Stanford University School of Medicine. Her research focuses on finding ways to improve maternal and infant health. Exposure themes include nutrition, social context, care, environmental contaminants and genetics. Outcome themes include severe maternal morbidity, stillbirth, birth defects, and preterm delivery. She is particularly interested in understanding the intersectionality of these varied types of exposures and outcomes and how they interact to impact health and health disparities, for the mother-baby dyad.
John A. Turner Endowed Professor for Child and Adolescent Psychiatry
Current Research and Scholarly Interests Examines the interplay between brain development and stress vulnerability via a multi-method approach that includes psychophysiology, neuroimaging, neuroendocrinology and phenomenology. Treatment development that focuses on individual and community-based interventions for stress related conditions in children and adolescents that experience traumatic stress.
Clinical Associate Professor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests My research pursuits are focused on system based improvement projects. At Lucile Packard Children's Hospital Stanford, I use system based approaches to improve the quality of care patients receive in the perioperative area and in the ICUs, with a focus on safe transitions of care. Through the Department of Graduate Medical Education at Stanford School of Medicine, I advise residency and fellowship programs on evidence based methods to improve their programs, with a focus on mentorship.
Professor of Anesthesiology, Perioperative and Pain Medicine (Adult MSD) at the Stanford University Medical Center
Current Research and Scholarly Interests My main research interest is in clinical and translational research related to cesarean delivery and labor analgesia as well as maternal-fetal pharmacokinetics and pharmacodynamics drug modeling.
Instructor, Pediatrics - Stem Cell Transplantation
Bio Dr. Cepika is an immunologist with an extensive background in translational research, autoimmunity, autoinflammation, and human systems immunology. Her goal is to understand the mechanisms governing immunological tolerance, and to leverage this knowledge to cure currently incurable diseases.
Dr. Cepika received her MD degree and a PhD in Immunology from the University of Zagreb School of Medicine in Croatia. There, she focused on the immunomonitoring of patients with lupus, identifying how circulating DNA levels changed with therapy. Subsequently, she joined the lab of Dr. Virginia Pascual at the Baylor Institute for Immunology Research in Dallas, Texas. Dr. Pascual had previously discovered that IL-1beta is a key pathogenic player in systemic juvenile idiopathic arthritis (sJIA), but the immune alterations contributing to IL-1beta-mediated inflammation remained unknown. To address this, Dr. Cepika developed a 3D in vitro stimulation assay to evaluate immune responses of blood leukocytes of pediatric sJIA patients. In combination with integrated bioinformatics analysis, this approach identified aberrant cellular responses, transcriptional pathways and genes that shed new light on immune dysregulation in sJIA. This assay can be further applied to dissect underlying immunopathogenic mechanisms in many human disorders.
Currently, Dr. Cepika is a member of the laboratory of Dr. Maria Grazia Roncarolo, in the Pediatric Division of Stem Cell Biology and Regenerative Medicine at Stanford University School of Medicine. There, she is working to uncover the underlying mechanisms governing type 1 regulatory T (Tr1) cell differentiation and function, and use this knowledge to design Tr1 cell-based therapies for hematopoietic stem cell transplantation and cancer immunotherapy.
Anne Lynn S. Chang, MD
Professor of Dermatology at the Stanford University Medical Center
Current Research and Scholarly Interests I have two main research interests:
1) to better understand and treat patients with aggressive basal and squamous cell carcinomas
2) to better understand the genetic and epigenetic mechanisms of healthy human skin aging and to translate these insights into better care of skin diseases enriched in older patients particularly skin cancer and rosacea
Howard Y. Chang, MD, PhD
Virginia and D. K. Ludwig Professor of Cancer Genomics and of Genetics
Current Research and Scholarly Interests Our research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.
Assistant Professor of Surgery (Pediatric Surgery) at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Chao's research focuses on preventing surgical diseases minimizing the impact of surgery. She works with the Asian Liver Center towards the global eradication of hepatitis B, the leading cause of liver cancer and liver disease globally. Dr. Chao helped launch the Jade Ribbon Campaign in 2001 to improve public and physician awareness about hepatitis B. Dr. Chao also serves as the Trauma Medical Director of LPCH and is interested in preventing pediatric traumatic injuries.
Assistant Professor of Anesthesiology, Perioperative and Pain Medicine (Pediatric) at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Char's research is focused on identifying and addressing ethical concerns associated with the implementation of next generation technologies like whole genome sequencing and its attendant technologies like machine learning to bedside clinical care.
Bertha Chen, MD
Professor of Obstetrics and Gynecology (Gynecology - Urogynecology) and, by courtesy, of Urology at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Chen?s research examines the molecular causes of urinary incontinence and pelvic floor dysfunction. Recognizing that urinary incontinence linked to demise of smooth muscle sphincter function, she is investigating the potential use of stem cell regeneration to restore muscle capacity.
James K. Chen
Jauch Professor and Professor of Chemical and Systems Biology, of Developmental Biology and of Chemistry
Current Research and Scholarly Interests Our laboratory combines chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis. We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development.