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1. Use of an administrative database (UNOS) to study lung transplant outcomes.<br/>2. Expression of the plasminogen activator inhibitor (PAI) 1 antibody in peripheral blood after lung transplantation and its association with bronchiolitis obliterans syndrome (chronic rejection).<br/>3. Impact of airway hypoxia, due to lack of bronchial circulation, on long-term lung transplant outcomes.<br/>4. CMV specific T-cell immunity in lung transplant recipients and its impact on acute rejection.