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Felix Boos
Basic Life Research Scientist, Genetics
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Publications (19)
All Publications
(19)
Featured Publications
(6)
Journal Articles
(19)
Profiles With Related Publications
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Joseph David Allen
MD Student with Scholarly Concentration in Molecular Basis of Medicine / Surgery, expected graduation Spring 2028
6
Total Publications
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Patrick O. Brown
Professor of Biochemistry, Emeritus
Research Interests
Replacing humanity's most destructive invention - the use of animals as a food technology - by developing a new and better way to produce the world's most delicious, nutritious and affordable meats, fish and dairy foods directly from plants.
Developing a scalable system for producing a high-quality soluble protein from leaves.
Experimental study of ecosystem restoration on land degraded by cattle grazing.
323
Total Publications
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Jingxun Chen
Basic Life Research Scientist, Genetics
13
Total Publications
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Raymond Chen
Lead Undergraduate Advising Director, Academic Advising Operations
8
Total Publications
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Mike Cherry
Professor (Research) of Genetics, Emeritus
Research Interests
My research involves identifying, validating and integrating scientific facts into encyclopedic databases essential for research and scientific education. Published results of scientific experimentation are a foundation of our understanding of the natural world and provide motivation for new experiments. The combination of in-depth understanding reported in the literature with computational analyses is an essential ingredient of modern biological research.
155
Total Publications
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Martha S. Cyert
Dr. Nancy Chang Professor
Research Interests
The Cyert lab is identifying signaling networks for calcineurin, the conserved Ca2+/calmodulin-dependent phosphatase, and target of immunosuppressants FK506 and cyclosporin A, in yeast and mammals. Cell biological investigations of target dephosphorylation reveal calcineurin’s many physiological functions. Roles for short linear peptide motifs, or SLiMs, in substrate recognition, network evolution, and regulation of calcineurin activity are being studied.
71
Total Publications
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Hunter Fraser
Professor of Biology
Research Interests
We study the evolution of complex traits by developing new experimental and computational methods.
Our work brings together quantitative genetics, genomics, epigenetics, and evolutionary biology to achieve a deeper understanding of how genetic variation shapes the phenotypic diversity of life. Our main focus is on the evolution of gene expression, which is the primary fuel for natural selection. Our long-term goal is to be able to introduce complex traits into new species via genome editing.
90
Total Publications
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Judith Frydman
Donald Kennedy Chair in the School of Humanities and Sciences and Professor of Genetics
Research Interests
The long term goal of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether reengineering chaperone networks can provide therapeutic strategies.
196
Total Publications
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Aaron D. Gitler
Stanford Medicine Basic Science Professor
Research Interests
We investigate the mechanisms of human neurodegenerative diseases, including Alzheimer disease, Parkinson disease, and ALS. We don't limit ourselves to one model system or experimental approach. We start with yeast, perform genetic and chemical screens, and then move to other model systems (e.g. mammalian tissue culture, mouse, fly) and even work with human patient samples (tissue sections, patient-derived cells, including iPS cells) and next generation sequencing approaches.
205
Total Publications
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Sarah Huang
Program Manager, Medicine - Med/Cardiovascular Medicine Research Data Analyst 1, Medicine - Med/Cardiovascular Medicine
6
Total Publications
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Daniel Jarosz
Senior Associate Dean, Basic Science, Professor of Chemical and Systems Biology and of Developmental Biology
Research Interests
My laboratory studies conformational switches in evolution, disease, and development. We focus on how molecular chaperones, proteins that help other biomolecules to fold, affect the phenotypic output of genetic variation. To do so we combine classical biochemistry and genetics with systems-level approaches. Ultimately we seek to understand how homeostatic mechanisms influence the acquisition of biological novelty and identify means of manipulating them for therapeutic and biosynthetic benefit.
77
Total Publications
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Ron Kopito
Professor of Biology
Research Interests
Our laboratory use state-of-the-art cell biological, genetic and systems-level approaches to understand how proteins are correctly synthesized, folded and assembled in the mammalian secretory pathway, how errors in this process are detected and how abnormal proteins are destroyed by the ubiquitin-proteasome system.
131
Total Publications
Publication Topics For This Person
Cytosol
Gene Expression Regulation, Fungal
Genome, Fungal
Genomic Library
Green Fluorescent Proteins
Heat-Shock Proteins
Heat-Shock Response
Kinetics
Membrane Proteins
Methionine
Mice, Inbred C57BL
Mice, Knockout
Microtubule-Associated Proteins
Mitochondria
Mitochondrial Membrane Transport Proteins
Mitochondrial Proteins
Models, Biological
NADH Dehydrogenase
Nuclear Proteins
Oxidative Phosphorylation
Palmitoyl-CoA Hydrolase
Peptides
Promoter Regions, Genetic
Proteasome Endopeptidase Complex
Protein Binding
Protein Transport
Proteome
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Stress, Physiological