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Erin Gibson received her Bachelors of Science from Duke University in 2005 majoring in Psychology/Neuroscience. She received her PhD under Dr. Lance Kriegsfeld at the University of California, Berkeley in 2011 studying the role of the circadian system in homeostatic processes, including neuroendocrine, immune and neural stem cell regulation. As a postdoctoral scholar in the lab of Dr. Michelle Monje at Stanford University, Dr. Gibson studied the effect of in vivo neuronal activity on myelin microstructure in health and disease such as the dysmyelinating disorder associated with chemotherapy-related cognitive impairment. Her lab focuses on understanding how glial cells modulate neural circuits throughout development and in diseases such as autism, multiple sclerosis, and chemotherapy-related cognitive impairment. The Gibson lab aims to discern how the circadian system influences glial form and function throughout life.
The Gibson Lab studies the cellular and molecular mechanisms modulating glia. One molecular mechanism that affords cells a dynamical nature is the circadian clock. While much is known about how the circadian clock influences neurons and peripheral cells throughout the body, little is known about how this core molecular mechanism regulates glia. We study how the circadian clock system regulates glial function to better understand diseases of the nervous system in which both circadian/sleep and glial dysfunction are prominent, such as autism, multiple sclerosis, and chemotherapy-related cognitive impairment.<br/><br/>•What cellular processes in glia are regulated by the circadian system?<br/>•What is the function of the circadian clock system during myelination?<br/>•How does the circadian clock machinery influence myelin-forming cell structure and function?<br/>•How does disruption in the circadian clock affect diseases of dysregulated myelination?<br/>•How do circadian disruptions mediated by environmental changes (i.e. jet lag, shift work, light at night) affect brain form and function in health and disease?