Eric Meffre

Professor of Medicine (Immunology and Rheumatology)

Academic Appointments

Professor, Medicine - Immunology & Rheumatology
Member, Maternal & Child Health Research Institute (MCHRI)

All Publications

Publications (42)

All Publications (42)
Featured Publications (4)
Journal Articles (38)
Conference Proceedings (4)

Profiles With Related Publications

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Ash A. Alizadeh, MD/PhD

Moghadam Family Professor
Clinical Focus
Cancer > Lymphoma, Lymphoma, B-Cell Chronic Lymphocytic Leukemia, Waldenstrom Macroglobulinemia, Burkitt Lymphoma, Follicular Lymphoma, Diffuse Large-Cell Lymphomas, Leukemia, Hairy Cell, Lymphoma, B-Cell, Marginal Zone, Hodgkin Disease, Medical Oncology
Research Interests
My research is focused on attaining a better understanding of the initiation, maintenance, and progression of tumors, and their response to current therapies toward improving future treatment strategies. In this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.

Clinically, I specialize in the care of patients with lymphomas, working on translating our findings in prospective cancer clinical trials.

380 Total Publications
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Rosa Bacchetta

Associate Professor (Research) of Pediatrics (Stem Cell Transplantation)

58 Total Publications
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Sean Bendall

Associate Professor of Pathology
Research Interests
Our goal is to understand the mechanisms regulating the development of human systems. Drawing on both pluripotent stem cell biology, hematopoiesis, and immunology, combined with novel high-content single-cell analysis (CyTOF – Mass Cytometry) and imagining (MIBI-Multiplexed Ion Beam Imaging) we are creating templates of ‘normal’ human cellular behavior to both discover novel regulatory events and cell populations as well as understand dysfunctional processes such as cancer.

153 Total Publications
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Scott D. Boyd, MD PhD

Stanford Professor of Food Allergy and Immunology and Professor of Pathology
Clinical Focus
Hematopathology, Clinical Chemistry
Research Interests
Our goal is to understand the lymphocyte genotype-phenotype relationships in healthy human immunity and in immunological diseases. We apply new technologies and data analysis approaches to this challenge, particularly high-throughput DNA sequencing and single-cell monoclonal antibody generation, in parallel with other functional assays.

137 Total Publications
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Alma-Martina Cepika

Instructor, Pediatrics - Stem Cell Transplantation

37 Total Publications
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Gerald Crabtree

David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Research Interests
Chromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.

262 Total Publications
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Edgar Engleman

Professor of Pathology and of Medicine (Immunology and Rheumatology)
Research Interests
Dendritic cells, macrophages, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer, autoimmune disease, neurodegenerative disease and metabolic disease.

286 Total Publications
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C. Garrison Fathman

Professor of Medicine (Immunology and Rheumatology), Emeritus
Research Interests
My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity. We have identified and characterized a gene (GRAIL) that seems to control regulatory T cell (Treg) responsiveness by inhibiting the Treg IL-2 receptor desensitization. We have characterized a gene (Deaf1) that plays a major role in peripheral tolerance in T1D. Using PBC gene expression, we have provisionally identified a signature of risk and progression in T1D.

326 Total Publications
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Jorg Goronzy

Professor of Medicine (Immunology and Rheumatology), Emeritus

479 Total Publications
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Ronald Levy, MD

Robert K. and Helen K. Summy Professor in the School of Medicine
Clinical Focus
Cancer > Lymphoma, Lymphoma , Non-Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma - Medical Oncology, Burkitt's Lymphoma, Burkitt's Lymphoma - Medical Oncology, Hodgkin's Disease, Hodgkin's Disease - Medical Oncology, Burkitt's Lymphoma - Hematology, Hodgkin's Disease - Hematology, Oncology (Cancer), Non-Hodgkin's Lymphoma - Hematology, Medical Oncology
Research Interests
Clinical Interests: lymphoma. Research Interests: Immunology and molecular biology of lymphoid malignancy; molecular vaccines for cancer.

417 Total Publications
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David B. Lewis

Naddisy Foundation Professor of Pediatric Food Allergy, Immunology, and Asthma
Clinical Focus
Primary Immunodeficiency, Pediatrics
Research Interests
My laboratory is focused on defining cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies. We are also determinomg how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants for influenza vaccine and by using catalytically inactive Cas proteins for inducing endogenous gene expression.

174 Total Publications
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Crystal Mackall

Ernest and Amelia Gallo Family Professor and Professor of Pediatrics and of Medicine
Clinical Focus
Pediatric Hematology-Oncology
Research Interests
Recent clinical studies, by us and others, have demonstrated that genetically engineered T cells can eradicate cancers resistant to all other therapies. We are identifying new targets for these therapeutics, exploring pathways of resistance to current cell therapies and creating next generation platforms to overcome therapeutic resistance. We have discovered novel insights into the biology of human T cell exhaustion and developed approaches to prevent and reverse this phenomenon.

349 Total Publications