Djenet Bousbaine

Postdoctoral Scholar, Bioengineering

Professional Education

Doctor of Philosophy, Massachusetts Institute of Technology, Microbiology (2020)
Master of Science, Swiss Federal Institute of Technology (EPFL), Life Sciences and technologies (2012)
Bachelor of Science, Swiss Federal Institute of Technology (EPFL), Life Sciences and technologies (2010)

All Publications

Profiles With Related Publications

close
Gita Chu Abhiraman

MD Student, expected graduation Spring 2023 Ph.D. Student in Immunology, admitted Autumn 2020 MSTP Student

2 Total Publications
close
Thomas Christopher Beck

MD Student, expected graduation Winter 2024

7 Total Publications
close
Matthew Bogyo

Professor of Pathology and of Microbiology and Immunology and, by courtesy, of Chemical and Systems Biology
Research Interests
Our lab uses chemical, biochemical, and cell biological methods to study protease function in human disease. Projects include:

1) Design and synthesis of novel chemical probes for serine and cysteine hydrolases.

2) Understanding the role of hydrolases in bacterial pathogenesis and the human parasites, Plasmodium falciparum and Toxoplasma gondii.

3) Defining the specific functional roles of proteases during the process of tumorogenesis.

4) In vivo imaging of protease activity

349 Total Publications
close
Yueh-hsiu Chien

Professor of Microbiology & Immunology
Research Interests
Contribution of T cells to immunocompetence and autoimmunity; how the immune system clears infection, avoids autoimmunity and how infection impacts on the development of immune responses.

103 Total Publications
close
Elizabeth Egan

Assistant Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology
Clinical Focus
Pediatric Infectious Diseases
Research Interests
Malaria is a parasitic disease transmitted by mosquitos that is a leading cause of childhood mortality globally. Public health efforts to control malaria have historically been hampered by the rapid development of drug resistance. The goal of our research is to understand the molecular determinants of critical host-pathogen interactions in malaria, with a focus on the erythrocyte host cell. Our long-term goal is to develop novel approaches to prevent or treat malaria and improve child health.

29 Total Publications
close
C. Garrison Fathman

Professor of Medicine (Immunology and Rheumatology), Emeritus
Research Interests
My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity. We have identified and characterized a gene (GRAIL) that seems to control regulatory T cell (Treg) responsiveness by inhibiting the Treg IL-2 receptor desensitization. We have characterized a gene (Deaf1) that plays a major role in peripheral tolerance in T1D. Using PBC gene expression, we have provisionally identified a signature of risk and progression in T1D.

324 Total Publications
close
Chris Garcia

Younger Family Professor and Professor of Structural Biology
Research Interests
Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology. We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.

251 Total Publications
close
Lauren Higdon

Instructor, Medicine - Nephrology

20 Total Publications
close
Christine Jacobs-Wagner

Dennis Cunningham Professor and Professor of Biology

78 Total Publications
close
Patricia Jones

The Dr. Nancy Chang Professor, Emerita
Research Interests
Dr. Jones' research has focused on genetic, molecular, and cellular mechanisms that regulate immune responses. Recent work was centered on the regulation of innate immune responses that are triggered by conserved microbial components. As these responses can be harmful they are highly regulated in their occurrence, magnitude, and duration. Her lab discovered a novel mechanism that negatively regulates innate responses, mediated by the phosphatase calcineurin.

31 Total Publications
close
Christian Kunder

Clinical Associate Professor, Pathology
Clinical Focus
Anatomic Pathology, Surgical Pathology, Urological Pathology, Soft Tissue Pathology, Molecular Pathology

90 Total Publications
close
Shoshana Levy

Professor (Research) of Medicine (Oncology)
Research Interests
Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria.

129 Total Publications