Djenet Bousbaine

Postdoctoral Scholar, Bioengineering

Profesional Education

Doctor of Philosophy, Massachusetts Institute of Technology, Microbiology (2020)
Master of Science, Swiss Federal Institute of Technology (EPFL), Life Sciences and technologies (2012)
Bachelor of Science, Swiss Federal Institute of Technology (EPFL), Life Sciences and technologies (2010)

All Publications

Profiles With Related Publications

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Gita Chu Abhiraman

MD Student, expected graduation Spring 2023 Ph.D. Student in Immunology, admitted Autumn 2020 MSTP Student

2 Total Publications
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Thomas Christopher Beck

MD Student, expected graduation Winter 2024

7 Total Publications
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Matthew Bogyo

Professor of Pathology and of Microbiology and Immunology and, by courtesy, of Chemical and Systems Biology
Research Interests
Our lab uses chemical, biochemical, and cell biological methods to study protease function in human disease. Projects include:

1) Design and synthesis of novel chemical probes for serine and cysteine hydrolases.

2) Understanding the role of hydrolases in bacterial pathogenesis and the human parasites, Plasmodium falciparum and Toxoplasma gondii.

3) Defining the specific functional roles of proteases during the process of tumorogenesis.

4) In vivo imaging of protease activity

304 Total Publications
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Yueh-hsiu Chien

Professor of Microbiology & Immunology
Research Interests
Contribution of T cells to immunocompetence and autoimmunity; how the immune system clears infection, avoids autoimmunity and how infection impacts on the development of immune responses.

102 Total Publications
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Elizabeth Egan

Assistant Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology
Clinical Focus
Pediatric Infectious Diseases
Research Interests
Malaria is a parasitic disease transmitted by mosquitos that is a leading cause of childhood mortality globally. Public health efforts to control malaria have historically been hampered by the rapid development of drug resistance. The goal of our research is to understand the molecular determinants of critical host-pathogen interactions in malaria, with a focus on the erythrocyte host cell. Our long-term goal is to develop novel approaches to prevent or treat malaria and improve child health.

24 Total Publications
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C. Garrison Fathman

Professor of Medicine (Immunology and Rheumatology), Emeritus
Research Interests
My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity. We have identified and characterized a gene (GRAIL) that seems to control regulatory T cell (Treg) responsiveness by inhibiting the Treg IL-2 receptor desensitization. We have characterized a gene (Deaf1) that plays a major role in peripheral tolerance in T1D. Using PBC gene expression, we have provisionally identified a signature of risk and progression in T1D.

324 Total Publications
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Chris Garcia

Younger Family Professor and Professor of Structural Biology
Research Interests
Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology. We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.

230 Total Publications
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Alex Gitlin

Instructor, Pathology
Clinical Focus
Pathology

21 Total Publications
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Leonore A. Herzenberg

Department of Genetics Flow Cytometry Professor
Research Interests
B-cell lineage development and function; IgH rearrangement and repertoire analysis; HSC and lymphoid stem cells and lineages in mouse and man; T cell regulation of antibody responses; glutathione regulation of lymphoid and myeloid subst functions; development of advanced methods and software for Fluorescence-Activated Cell Sorting (FACS) and related analyses.

361 Total Publications
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Lauren Higdon

Instructor, Medicine - Nephrology

15 Total Publications
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Christine Jacobs-Wagner

Dennis Cunningham Professor and Professor of Biology

77 Total Publications
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Patricia Jones

The Dr. Nancy Chang Professor, Emerita
Research Interests
Dr. Jones' research has focused on genetic, molecular, and cellular mechanisms that regulate immune responses. Recent work was centered on the regulation of innate immune responses that are triggered by conserved microbial components. As these responses can be harmful they are highly regulated in their occurrence, magnitude, and duration. Her lab discovered a novel mechanism that negatively regulates innate responses, mediated by the phosphatase calcineurin.

31 Total Publications