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Dr. McIlwain studies host-response to infectious disease using high dimensional single-cell and spatial proteomics tools. He trained for his Ph.D. at the University of Toronto exploring mouse biology using reverse genetics with renowned immunologist Dr. Tak W. Mak. His doctoral work yielded insights into alternative mRNA splicing and an important discovery about iRhom2 as a new factor controlling the production of inflammatory mediator TNF. As a post-doctoral fellow, Dr. McIlwain investigated host response to viral infection in animal models at the University of Dusseldorf in Germany before moving to Stanford University where along with Dr. Garry Nolan, he leads a team executing research contracted by the FDA’s medical countermeasures initiative to study emerging pathogens. This work includes mass cytometry (CyTOF) and spatial proteomic (CODEX) single-cell analysis of human and animal model influenza, Ebola, zika, and SARS-CoVs infections.