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Dr. Maron is Director of Preventive Cardiology. He is board certified in internal medicine, cardiovascular disease, and clinical lipidology. He was an undergraduate at Stanford, received his medical degree from University of Southern California, and completed his residency in internal medicine at UCLA. He completed a cardiology fellowship and a research fellowship in cardiovascular disease epidemiology and prevention at Stanford University as a Robert Wood Johnson Clinical Scholar. He was on the faculty at Vanderbilt for 20 years before returning to Stanford in 2014. His research is focused on primary and secondary prevention of coronary artery disease. He has extensive experience in multicenter clinical trials, serving as a member of the Executive Committee and Chair of the Optimal Medical Therapy Committee for the VA-funded COURAGE trial, and now as the PI and Co-Chair of the NHLBI-funded ISCHEMIA trial, and Co-Chair of the NHLBI-funded ISCHEMIA-CKD trial.
Dr. Maron is the Co-Chair and Principal Investigator of the ISCHEMIA trial, and Co-Chair of the ISCHEMIA-CKD trial. These large, international, NIH-funded studies will determine whether an initial invasive strategy of cardiac catheterization and revascularization plus optimal medical therapy will reduce cardiovascular events in patients with and without chronic kidney disease and at least moderate ischemia compared to an initial conservative strategy of optimal medical therapy alone.
Phase 2 Study of ISIS 681257 (AKCEA-APO(a)-LRx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease
This is a multicenter, randomized, double-blind, placebo-controlled, dose-ranging study to
evaluate the safety, including tolerability, of ISIS 681257 and to assess the efficacy of
different doses and dosing regimens of ISIS 681257 for reduction of plasma Lipoprotein(a)
[Lp(a)] levels in participants with hyperlipoproteinemia(a) and established cardiovascular
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