David Drover

Professor of Anesthesiology, Perioperative and Pain Medicine

Clinical Focus

Anesthesia for Liver Transplantation
Anesthesia for ENT Surgery
Difficult Airway
Neuroanesthesia
Anesthesia

Academic Appointments

Professor - University Medical Line, Anesthesiology, Perioperative and Pain Medicine
Member, Bio-X
Member, Maternal & Child Health Research Institute (MCHRI)
Member, Wu Tsai Neurosciences Institute

Profesional Education

Fellow, Stanford University, Biodesign Faculty Fellowship (2019)
Residency: Dalhousie University Residency Training (1995) Canada
Internship: Dalhousie University Residency Training (1991) Canada
Medical Education: Dalhousie University Medicine (1990)
Board Certification: Royal College of Physicians and Surgeons, Anesthesia (1995)
BSc, Dalhousie University, Science (1985)
MSc, Dalhousie University, Clinical Chemistry (1988)
MD, Dalhousie University, Medicine (1990)
FRCP(C), Dalhousie University, Anesthesia (1995)

Contact

Academic ddrover@stanford.edu Tel: (415) 606-6115Tel: (650) 725-0364 Fax: (650) 725-8544

Clinical Department of Anesthesia 300 Pasteur Dr MC 5117 Stanford CA 94305-5117 Tel: (650) 725-0364 Fax: (650) 725-8544

Current Research and Scholarly Interests

Field of clinical pharmacology. This involves analysis of what the body does to a drug (pharmacokinetics) and how exactly a specific drug affects the body (pharmacodynamics). His research starts at the level of new drug development with detailed analysis of the pharmacokinetics and pharmacodynamics of a medication.

Clinical Trials

Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient Recruiting
More
The research team is creating a foundational infrastructure in order to develop a precision medicine approach for geriatric patients who require surgery with anesthesia. The team plans to build the first of its kind comprehensive database of demographic and risk factor questionnaire responses, biobanked blood specimens, intraoperative electroencephalography (EEG), and inclusive cognitive testing throughout patient interaction starting at the preop appointment until a year later. This will be used to create a predictive model of periooperative neurocognitive disorders.

Lead Sponsor
- Stanford University
Stanford Investigators
- David Drover
View full details
Can Ondansetron Prevent Neonatal Abstinence Syndrome (NAS) in Babies Born to Narcotic-dependent Women Not Recruiting
More
The Investigators hope to learn if they can prevent or lessen the symptoms of neonatal abstinence syndrome (NAS) in babies born to narcotic-dependent mothers by using the drug ondansetron in the mothers prior to delivery and their babies after delivery. The study is a randomized, double-blind, placebo-controlled study with one half the mother-baby pairs to receive ondansetron and the other half of the mother-baby pairs to receive placebo. The pregnant narcotic-dependent mothers will receive an intravenous dose of study medication prior to delivery; the neonates, after their birth, will receive the same study medication the mother received every 24 hours for up to 5 days. The Investigators will follow up with the mother-baby pairs for 10 days after study drug has stopped and one last follow up, about 30 days after stopping study drug, to learn if the baby had any symptoms of NAS in that time period.

Stanford is currently not accepting patients for this trial. For more information, please contact Carol A Cohane, RN, .

Lead Sponsor
- Stanford University
Stanford Investigators
- David Drover
View full details
Pharmacokinetic (PK) and Pharmacodynamic (PD) Modeling of Ampicillin and Gentamicin in Peripartum Patients Not Recruiting
More
This study proposes to compare the metabolism of Ampicillin and Gentamicin by pregnant women to that of non-pregnant women; the placental transfer over time; and the subsequent metabolism of the transferred drug(s) in the neonate.

Stanford is currently not accepting patients for this trial. For more information, please contact Brendan Carvalho, MBBCh, 650-861-8607.

Lead Sponsor
- Stanford University
Stanford Investigators
- Brendan Carvalho
- David Drover
View full details
Correlate of Surface Electroencephalogram (EEG) With Implanted EEG Recordings (ECOG) Recruiting
More
Improve understanding of the correlation between surface EEG and implanted EEG recordings

Lead Sponsor
- Stanford University
Stanford Investigators
- David Drover
View full details
Measuring the Amount of Methadone or Morphine in the Blood of Neonates, Infants & Children After Cardiac Surgery. Not Recruiting
More
Study Population: Neonates, infants and children from birth to 5 years of age undergoing cardiac surgery with CPB. The use of methadone to provide analgesia may be increasing due to advantages compared to other commonly used opioid analgesic drugs. While efficacy of methadone has been reported in adults, there is a paucity of information in neonates and infants. In the latter population, fentanyl and morphine are most commonly used for opioid analgesia following major surgery, while methadone is frequently used for weaning of opioid dependent and tolerant patients, in spite of the paucity of knowledge of methadone pharmacology in this population. There are several clinical problems associated with fentanyl and morphine, and methadone may offer superior efficacy with fewer side effects than these agents. We propose to study the pharmacokinetics (PK) and pharmacodynamics (PD) of methadone in neonates and infants in the intensive care unit following cardiac surgery.

Stanford is currently not accepting patients for this trial. For more information, please contact Gregory Hammer, 6507237835.

Lead Sponsor
- Stanford University
Stanford Investigators
View full details
How Pregnant Women and Their Babies Metabolize Ondansetron Compared to a Group of Non-pregnant Women Not Recruiting
More
This is called "Aim 1" of the investigators' NIH grant. Ondansetron (Zofran) is a safe and effective drug used in pregnant women to prevent nausea but the investigators do not know what effect pregnancy may have on the metabolism of Zofran in pregnant women or their babies. Therefore the investigators will enroll approximately 40 pregnant women and their babies and draw blood samples from the mother, the baby and the cord, to determine how much Zofran is in each sample of blood (called the pharmacokinetics or PK of Zofran). The pregnant women will receive Zofran, as a standard-of-care drug, for their scheduled Cesarean Section. The investigators will also enroll about 20 non-pregnant women undergoing surgery who will receive Zofran as standard-of-care during surgery. In both the pregnant & the non-pregnant women, the investigators will draw blood samples at the same time points based on number of minutes from the time the Zofran is given. The blood data (PK of Zofran) will help the investigators move into Aim 2 of the study, which will be done in pregnant, narcotic-addicted mothers and their babies who are born addicted to narcotics. Aim 2 will be listed separately as it will be an interventional study.

Stanford is currently not accepting patients for this trial. For more information, please contact SPECTRUM, .

Lead Sponsor
- Stanford University
Stanford Investigators
- David Drover
View full details
Using the SEDLine for the Titration of Sevoflurane in Elderly Patients Recovery Using the SEDLine TM for the Titration of Sevoflurane in Elderly Patients Undergoing Non-Cardiac Surgery After Beta-Adrenergic Blockade Not Recruiting
More
Asses the effect of the use of Patient State Index (PSI) monitoring on difference in emergence profiles in the elderly (age >65 yrs) population to develop a cost-benefit profile. Assess differences in Quality of Life using the QoR-40 (a validated 40-item questionnaire on quality of recovery from anesthesia) between the two treatment groups.

Stanford is currently not accepting patients for this trial. For more information, please contact David Drover, 6507250364.

Lead Sponsor
- Stanford University
Stanford Investigators
- David Drover
- Cliff Schmiesing, MD
View full details

2021-22 Courses

Independent Studies
- Directed Reading in Anesthesiology
  ANES 299 (Aut, Win, Spr, Sum)
- Early Clinical Experience in Anesthesia
  ANES 280 (Aut, Win, Spr, Sum)
- Graduate Research
  ANES 399 (Aut, Win, Spr, Sum)
- Medical Scholars Research
  ANES 370 (Aut, Win, Spr, Sum)
- Undergraduate Research
  ANES 199 (Aut, Win, Spr, Sum)

Graduate and Fellowship Programs

Anesthesia (Fellowship Program)

All Publications

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