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Dr. Haeffele earned her medical degree from the Duke University School of Medicine in Durham, North Carolina. She completed a combined medicine and pediatric residency at Harvard University in Boston, Massachusetts at the Brigham and Women's Hospital and Boston Children's Hospital. She also completed the Doris and Howard Hiatt Residency in Global Health Equity and Internal Medicine program, working on oncology infrastructure in Rwanda in partnership with the Rwandan Ministry of Health and Partners in Health. She completed her fellowship in adult cardiology and sub-specialized training in adult congenital heart disease and echocardiography at Stanford Hospital. She served one year as a chief fellow for the general cardiology fellowship at Stanford. Dr. Haeffele is the Director of the Structural ECHO program at Stanford Hospital. She is an Assistant Program Director for the General Cardiology fellowship. Dr. Haeffele is also appointed Clinical Assistant Professor of Medicine and Pediatrics at Stanford University School of Medicine. Dr. Haeffele is a board certified cardiology physician. Her research interests include management of adults with congenital heart disease, structural heart disease and catheter based interventions, and the complexities of heart transplant in the adult with congenital heart disease.
Adult Congenital Heart Disease
Beating Heart Mitral Valve Repair With the HARPOON™ System
The objective of the study is to evaluate the safety and effectiveness of the HARPOON™ System
in the treatment of patients with severe degenerative mitral regurgitation (DMR).
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MitraClip REPAIR MR Study
The objective of this randomized controlled trial (RCT) is to compare the clinical outcome of
MitraClip™ device versus surgical repair in patients with severe primary MR who are at
moderate surgical risk and whose mitral valve has been determined to be suitable for
correction by MV repair surgery by the cardiac surgeon on the local site heart team.
Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial
To establish the safety and effectiveness of the Edwards PASCAL Transcatheter Valve Repair
System in patients with degenerative mitral regurgitation (DMR) who have been determined to
be at prohibitive risk for mitral valve surgery by the Heart Team, and in patients with
functional mitral regurgitation (FMR) on guideline directed medical therapy (GDMT)
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation
Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All
subjects enrolled with receive the study device.
CE Mark Study for the Harpoon Medical Device
The purpose of this study is to evaluate the safety and performance of the Harpoon Medical
device. It is anticipated, that the Harpoon Medical device will provide advantages over
current surgical interventions including: 1) a small minimally invasive incision, 2) no
sternotomy, 3) no cardiopulmonary bypass, 4) no aortic manipulation, 5) a direct path to the
valve plane, 6) performed on a beating heart, 7) real-time TOE-guided chordal length
adjustment and 8) less complicated procedure that is teachable and adoptable.
Stanford is currently not accepting patients for this trial.
For more information, please contact SPECTRUM, .
TRISCEND II Pivotal Trial
Pivotal trial to evaluate the safety and effectiveness of the Edwards EVOQUE tricuspid valve
2019-06 TRISCEND Study
Early feasibility study to assess safety and performance of the Edwards EVOQUE Tricuspid
Valve Replacement System
Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation
Prospective, controlled, multicenter clinical investigation with three trial cohorts:
Randomized, Non-Randomized, and Mitral Annular Calcification (MAC). Subjects in the
Randomized cohort will be randomized in a 1:1 ratio to the trial device or to the MitraClip
system. Subjects in the Non-Randomized and MAC cohorts will receive the trial device.
The objective of the Clinical Trial to Evaluate the Safety and Effectiveness of Using the
Tendyne Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation (SUMMIT) is
to evaluate the safety and effectiveness of the Tendyne Mitral Valve System for the treatment
of patients with symptomatic, moderate-to-severe or severe mitral regurgitation or for
patients with symptomatic mitral valve disease due to severe mitral annular calcification.
This randomized controlled trial will provide the opportunity to evaluate the safety and
clinical benefits of the Tendyne Mitral Valve System compared to the MitraClip System in
patients with symptomatic, moderate-to-severe or severe mitral regurgitation, within approved
MitraClip indications. In addition, the safety and effectiveness of the Tendyne Mitral Valve
System will be evaluated in patients with severe mitral annular calcification who are at
prohibitive risk for mitral valve surgery. Patients who are not suitable for mitral valve
surgery for reasons other than severe mitral annular calcification and are also not suitable
for transcatheter repair with MitraClip, will be enrolled in the Non-randomized cohort.
Subjects will be seen at screening, pre- and post-procedure, discharge, 30 days, 3 months, 6
months, and annually through 5 years.
ACURATE IDE: Safety and Efficacy Study of Acurate Valve for Transcatheter Aortic Valve Replacement
To evaluate safety and effectiveness of the ACURATE Transfemoral Aortic Valve System for
transcatheter aortic valve replacement (TAVR) in subjects with severe native aortic stenosis
who are indicated for TAVR.
Edwards CLASP TR EFS
Early feasibility study to assess the safety and performance of the Edwards PASCAL
Transcatheter Valve Repair System in tricuspid regurgitation