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Chih Long Liu
Sr. Research Scientist - Basic Life, Medicine - Med/Oncology
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Publications (20)
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Profiles With Related Publications
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Ash A. Alizadeh, MD/PhD
Moghadam Family Professor
Clinical Focus
Cancer > Lymphoma, Lymphoma, B-Cell Chronic Lymphocytic Leukemia, Waldenstrom Macroglobulinemia, Burkitt Lymphoma, Follicular Lymphoma, Diffuse Large-Cell Lymphomas, Leukemia, Hairy Cell, Lymphoma, B-Cell, Marginal Zone, Hodgkin Disease, Medical Oncology
Research Interests
My research is focused on attaining a better understanding of the initiation, maintenance, and progression of tumors, and their response to current therapies toward improving future treatment strategies. In this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.
Clinically, I specialize in the care of patients with lymphomas, working on translating our findings in prospective cancer clinical trials.
412
Total Publications
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Patrick O. Brown
Professor of Biochemistry, Emeritus
Research Interests
Dr. Brown's research focuses on replacing humanity's most destructive invention - the use of animals as a food technology - by developing a new and better way to produce the world's most delicious, nutritious and affordable meats, fish and dairy foods directly from plants. He is also working on developing and scaling optimal methods for restoring healthy ecosystems and sequestering carbon on the 45% of Earth's surface that have been devastated by animal agriculture.
319
Total Publications
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Douglas L. Brutlag
Professor of Biochemistry, Emeritus
Research Interests
My primary interest is to understand the flow of information from the genome to the phenotype of an organism. This interest includes predicting the structure and function of genes and proteins from their primary sequence, predicting function from structure simulating protein folding and ligand docking, and predicitng disease from genome variations. These goals are the same as the goals of molecular biology, however, we use primarily computational approaches.
105
Total Publications
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Dennis J Bua
Administrative Co-Director, School of Medicine - IDP's - MSTP
8
Total Publications
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Howard Y. Chang, MD, PhD
Virginia and D. K. Ludwig Professor of Cancer Research, Professor of Genetics and, by courtesy, of Pathology
Clinical Focus
Cancer > Cutaneous (Dermatologic) Oncology, Dermatology, General Dermatology
Research Interests
Our research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.
491
Total Publications
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Mike Cherry
Professor (Research) of Genetics, Emeritus
Research Interests
My research involves identifying, validating and integrating scientific facts into encyclopedic databases essential for research and scientific education. Published results of scientific experimentation are a foundation of our understanding of the natural world and provide motivation for new experiments. The combination of in-depth understanding reported in the literature with computational analyses is an essential ingredient of modern biological research.
146
Total Publications
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Katrin Chua
Professor of Medicine (Endocrinology, Gerontology and Metabolism)
51
Total Publications
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Gerald Crabtree
David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Research Interests
Chromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.
265
Total Publications
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Jesse Engreitz
Assistant Professor of Genetics
Research Interests
Regulatory elements in the human genome harbor thousands of genetic risk variants for common diseases and could reveal targets for therapeutics — if only we could map the complex regulatory wiring that connects 2 million regulatory elements with 21,000 genes in thousands of cell types in the human body.
We combine experimental and computational genomics, biochemistry, molecular biology, and genetics to assemble regulatory maps of the human genome and uncover biological mechanisms of disease.
65
Total Publications
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Andrew Gentles
Associate Professor (Research) of Pathology and of Medicine (BMIR)
115
Total Publications
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Or Gozani
Dr. Morris Herzstein Professor
Research Interests
We study the molecular mechanisms by which chromatin-signaling networks effect nuclear and epigenetic programs, and how dysregulation of these pathways leads to disease. Our work centers on the biology of lysine methylation, a principal chromatin-regulatory mechanism that directs epigenetic processes. We study how lysine methylation events are generated, sensed, and transduced, and how these chemical marks integrate with other nuclear signaling systems to govern diverse cellular functions.
122
Total Publications
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Siva Kasinathan
Fellow in Pediatrics - Rheumatology
Clinical Focus
Rheumatology, Pediatrics, Fellow
17
Total Publications
Publication Topics For This Person
Biomarkers, Tumor
Chromatin Immunoprecipitation
Cluster Analysis
DNA, Fungal
DNA-Binding Proteins
Gene Expression Profiling
Gene Expression Regulation, Fungal
Genes, Fungal
Genome
Genome, Fungal
Histones
Immunohistochemistry
Internet
Keratins
Lysine
Neoplasm Proteins
Neoplasms
Nucleosomes
Oligonucleotide Array Sequence Analysis
Promoter Regions, Genetic
Protein Array Analysis
Protein Binding
RNA, Messenger
Reproducibility of Results
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Signal Transduction
Tissue Array Analysis
Transcription Factors
Transcription, Genetic