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Charles Prober, MD is the Founding Executive Director of the Stanford Center for Health Education and Senior Associate Vice Provost for Health Education at Stanford University. He is a Professor of Pediatrics, Microbiology and Immunology. He is an expert in pediatric infectious diseases with an academic career focused on the epidemiology, pathophysiology, prevention, and treatment of infections in children. Some of his seminal work has resulted in the improvement of international blood transfusion practices through the selection of CMV negative donors for immunocompromised hosts; the optimal duration of antibiotic therapy for serious bacterial infections, including osteomyelitis and meningitis; the use of antiviral agents in the management of serious herpes virus infections; and the standardization of care in the management of pregnant women with HSV infections and their newborn infants. Prober has published extensively in peer-reviewed subspecialty, specialty, and general medical journals and he is editor of Principles and Practice of Pediatric Infectious Diseases, one of the major textbooks in the field of pediatric infectious diseases. Dr. Prober has been involved in medical education throughout his career. He has directed a number of undergraduate and graduate student courses in the classroom and at the bedside, He has served as Associate Chair for Education for the Department of Pediatrics and Senior Associate Dean for Medical Education at the School of Medicine (2007-2017). He has lectured locally, nationally, and internationally on infectious diseases and medical education.
My research interest is in the epidemiology, pathophysiology, prevention, and treatment of infections in children. Much of this research has focused on viral infections, especially those caused by herpes simplex virus (HSV). I have conducted a number of studies concerned with the epidemiology of HSV-2 infections in pregnant women, their partners, and neonates. I also have conducted studies on the immunologic response to HSV infections, including humoral and cell mediated responses. Furthermore, I have participated in a number of studies evaluating optimal therapy of HSV infections in pregnant women and neonates and HSV vaccine protocols. My interest in antiviral therapy extends beyond HSV infections; I have been involved in a number of studies of therapy for respiratory viral and HIV infections. My interest in bacterial infections includes the evaluation of a number of antibacterial agents (Phase I-III studies). I also am interested in the evaluation and management of infections in compromised hosts including neonates, transplant and chemotherapy recipients. I also am interested in developing interventions to reduce the inappropriate utilization of antimicrobial agents in ambulatory and hospital environments.I have a long-standing interest in medical education and currently serve as Senior Associate Dean for Medical Education at Stanford.
The Philani Mobile Video Intervention for Exclusive Breastfeeding (MOVIE) Study
This cluster-randomized controlled trial seeks to evaluate the impact of a mobile video
intervention for exclusive breastfeeding (MOVIE) on the infant feeding practices of mothers
living in under-resourced communities in the Western Cape, South Africa. The trial will
compare infant feeding practices in two groups of participants, enrolled in the Philani
Mentor-Mother Outreach Program, a home-visiting program focused on community-based health
promotion through peer-to-peer counseling. The participants in the intervention arm will
receive the Philani Intervention Model (PIM), a perinatal health promotion intervention,
together with the additional mobile, video intervention for exclusive breastfeeding. The
participants in the control arm will receive only the standard PIM. Participants will be
exposed to either the intervention or the control condition during pregnancy and the first
five months after delivery. The central hypothesis in this trial is that, when compared with
the control group, infant feeding practices in the intervention group will be significantly
better aligned with current World Health Organization recommendations, after exposure to the
Philani MOVIE intervention. The primary outcomes in this study are short-term exclusive
breastfeeding, in the first month of life, and long-term exclusive breastfeeding, in the
fifth month of life, (based on maternal 24-hour recall). Secondary outcomes include other
infant feeding practices, such as early initiation of breastfeeding, any breastfeeding in the
first month and in the fifth month of life, bottle-feeding, early introduction of
complementary foods in the first month and in the fifth month of life and maternal knowledge
in the first month and the fifth month post delivery.
Stanford is currently not accepting patients for this trial.
For more information, please contact SPECTRUM, .
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