Current Research and Scholarly Interests
Dr. Lipson's prior research activities focused on radiation dose with CT and the associated risk of cancer. As an NIH-funded T32 Research Fellow under the mentorship of Dr. Rebecca Smith-Bindman, Dr. Lipson conducted a study of four Bay Area hospitals in which she reviewed 1,200 CT examinations and CT radiation dose reports; estimated the effective dose from each examination; and calculated the associated risk of cancer attributable to that effective dose. Her study culminated in an article entitled "Radiation Dose Associated with Common Computed Tomography Examinations and the Associated Lifetime Attributable Risk of Cancer" (Arch Intern Med. 2009 Dec 14;169(22):2078-86), which is one of only a few articles that have raised national attention regarding the issue of medical radiation and the need for clinical practice guidelines to track and reduce dose.
Dr. Lipson's current research interests include the classification and quantification of dynamic contrast enhanced breast MRI patterns of response to poly ADP-ribose polymerase (PARP) inhibitor therapy in the neoadjuvant treatment of triple-negative and BRCA-associated breast cancer; the evaluation of mammographic density and breast cancer risk; early breast cancer detection using contrast enhanced spectral mammography, digital breast tomosynthesis, and high resolution breast MRI; and identifying new molecular imaging biomarkers of cancer burden and neoadjuvant chemotherapy response.