Bruce Koch, Ph.D.

Director, High-Throughput Screening

Current Role at Stanford

Head, ChEM-H/CSB High Throughput Screening Knowledge Center (HTSKC)
Staff Co-lead, IMA HTS Module

Adviser to the SPARK Program

Supervisors

Carolyn Bertozzi

Academic Appointments

Senior Research Scientist, Sarafan ChEM-H

Boards, Advisory Committees, Professional Organizations

Committee Member, NIH Study Section (Drug Discovery for Aging, Neuropsychiatric and Neurologic Disorders (SBIR/STTR)) (2014 - 2018)
Committee Member, NIH Study Section (NIH Roadmap HTS Assay for MLPCN R03) (2010 - 2010)
Committee Member, NIH Study Section (NIH Roadmap Assay Development R25) (2009 - 2009)
Committee Member, National Academy of Sciences Ohio BRTT Committee (2003 - 2003)
Member, Biophysical Society (1995 - Present)
Member, Society for Laboratory Automation and Screening (1999 - Present)
Member, Association of Biomolecular Resource Facilities (2012 - Present)

Professional Education

Post-doc, UC Berkeley, Biochemistry (PI: Randy Schekman)
Ph.D., Harvard Medical School, Cell and Developmental Biology (1986)
B.S., Bates College, Biology (1979)

Patents

P.S. Dietrich, B. Koch, H. Guthrie, U. A. Gubler. "United States Patent 8,349,572 Stable cell lines expressing hERG", Roche Palo Alto LLC, Jan 8, 2013
P.S. Dietrich, B. Koch, H. Guthrie, U. A. Gubler. "United States Patent 7,776,590B2 Stable cell lines expressing hERG", Roche Palo Alto LLC, Aug 17, 2010

All Publications

Profiles With Related Publications

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Timothy Angelotti MD, PhD

Clinical Associate Professor, Anesthesiology, Perioperative and Pain Medicine
Clinical Focus
Critical Care, Anesthesia
Research Interests
My research efforts are focused on investigating the pharmacological and physiological interface of the autonomic nervous system with effector organs. Utilizing molecular, cellular, and electrophysiological techniques, we are examining alpha2 adrenergic receptor function in cultured sympathetic neurons. Future research aims will be directed toward understanding neurotransmitter release in general.

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Edward Bertaccini

Professor of Anesthesiology, Perioperative and Pain Medicine
Research Interests
molecular modeling of anesthetic-protein interactions, molecular modeling of the ligand-gated ion channels

88 Total Publications
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Patrick O. Brown

Professor of Biochemistry, Emeritus
Research Interests
Dr. Brown's research focuses on replacing humanity's most destructive invention - the use of animals as a food technology - by developing a new and better way to produce the world's most delicious, nutritious and affordable meats, fish and dairy foods directly from plants. He is also working on developing and scaling optimal methods for restoring healthy ecosystems and sequestering carbon on the 45% of Earth's surface that have been devastated by animal agriculture.

319 Total Publications
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William Clusin, MD

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Research Interests
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53 Total Publications
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James Ferrell

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My lab has two main goals: to understand the regulation of mitosis and to understand the systems-level logic of simple signaling circuits. We often make use of Xenopus laevis oocytes, eggs, and cell-free extracts for both sorts of study. We also carry out single-cell fluorescence imaging studies on mammalian cell lines. Our experimental work is complemented by computational and theoretical studies aimed at understanding the design principles and recurring themes of regulatory circuits.

153 Total Publications
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Uta Francke

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Clinical Focus
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Research Interests
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565 Total Publications
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Rona Giffard

Professor of Anesthesiology, Perioperative and Pain Medicine, Emerita
Research Interests
Astrocytes, microglia and neurons interact, and have unique vulnerabilities to injury based on their patterns of gene expression and their functional roles. We focus on the cellular and molecular basis of brain cell injury in stroke. We study the effects of altering miRNA expression, altering levels of heat shock and cell death regulatory proteins. Our goal is to improve outcome by improving mitochondrial function and brain cell survival, and reducing oxidative stress and inflammation.

179 Total Publications
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Miriam B. Goodman

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112 Total Publications
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Brian Hoffman

Professor of Medicine (Endocrinology, Gerontology and Metabolism), Emeritus

154 Total Publications
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John Huguenard

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Research Interests
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Mary Hynes

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Ron Kopito

Professor of Biology
Research Interests
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129 Total Publications