School of Medicine
Showing 41-50 of 50 Results
Ahmad Salehi Najaf Abadi
Adjunct Professor, Psych/Public Mental Health & Population Sciences
Bio Dr. Salehi is a neurobiologist working on identifying molecular mechanisms of neurodegenerative disorders including Alzheimer's disease and Down syndrome. In this process, he uses pre-clinical experiments to test the effects of already-approved drugs in improving cognitive function in the mouse models with hippocampal degeneration. In 2010, he received the World Technology Award for the innovative use of mouse models of Down syndrome to identify genes responsible for cognitive disabilities. Recently, he found that increasing beta2 adrenergic signaling would improve cognitive function in a mouse model of Down syndrome. Accordingly, in a collaborative study, he is testing whether already-approved beta2-adrenergic receptor agonists can indeed improve cognitive function and reduce the severity of pathology in individuals with mild to moderate Alzheimer’s disease.
Dang V, Medina B, Das D, Moghadam S, Martin KJ, Lin B, Naik P, Patel D, Nosheny R, Wesson Ashford J, Salehi A. Formoterol, a long-acting β2 adrenergic agonist, improves cognitive function and promotes dendritic complexity in a mouse model of Down syndrome. Biol Psychiatry. 2014 Feb 1;75(3):179-88. doi: 10.1016/j.biopsych.2013.05.024. PMID: 23827853
Salehi A, Faizi M, Colas D, Valletta J, Laguna J, Takimoto-Kimura R, Kleschevnikov A, Wagner SL, Aisen P, Shamloo M, Mobley WC. Restoration of norepinephrine-modulated contextual memory in a mouse model of Down syndrome. Sci Transl Med. 2009 Nov 18;1(7):7ra17. doi: 10.1126/scitranslmed.3000258. PMID: 20368182
Salehi A, Delcroix JD, Belichenko PV, Zhan K, Wu C, Valletta JS, Takimoto-Kimura R, Kleschevnikov AM, Sambamurti K, Chung PP, Xia W, Villar A, Campbell WA, Kulnane LS, Nixon RA, Lamb BT, Epstein CJ, Stokin GB, Goldstein LS, Mobley WC. Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration. Neuron. 2006 Jul 6;51(1):29-42. PMID: 16815330
Salehi A, Delcroix JD, Belichenko PV, Zhan K, Wu C, Valletta JS, Takimoto-Kimura R, Kleschevnikov AM, Sambamurti K, Chung PP, Xia W, Villar A, Campbell WA, Kulnane LS, Nixon RA, Lamb BT, Epstein CJ, Stokin GB, Goldstein LS, Mobley WC.Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.
Neuron. 2006 Jul 6;51(1):29-42.
Blake K. Scanlon, Ph.D.
Clinical Assistant Professor (Affiliated) [Vapahcs], Psych/Public Mental Health & Population Sciences
Bio The overarching aim of Dr. Scanlon’s research is to develop and evaluate low-cost, pragmatic and clinically translatable methods for improving management of neurodegenerative disease and dementia. To that end, the Caregiver Technology Division of the Scanlon Lab aims to enhance patient- and family-centered care through novel, broadly customizable, and highly scalable caregiver interventions. In parallel, the Neurodegenerative Division of the Scanlon Lab focuses on the development and application of cognitive, neuropsychiatric, and biological markers for the initiation and progression of neurodegeneration.
Dr. Scanlon received his bachelor’s degree in Neuroscience and doctorate in Clinical Health Psychology from the University of Miami. After concluding his clinical internship in Geropsychology/Neuropsychology at the VA Palo Alto Health Care System (VAPAHCS), he completed fellowships in Aging and Dementia at Stanford University School of Medicine and VAPAHCS. Dr. Scanlon is currently a VA Career Development Awardee in the Sierra-Pacific Mental Illness Research, Education, and Clinical Center (MIRECC) and Stanford/VA Aging Clinical Research Center where his work focuses on developing and evaluating low-cost, pragmatic and clinically translatable methods for improving management of neurodegenerative disease and dementia. He also serves as Co-Director of the Stanford/VA California Alzheimer's Disease Center, Chair of the VAPAHCS Dementia Committee, and Co-Chair of the Department of Veterans Affairs VISN 21 Dementia Committee.
Clinical Rsch Coord 2, Psych/Public Mental Health & Population Sciences
Current Role at Stanford Clinical Research Coordinator for the BITS Study which tests the feasibility of adding ten in-home decluttering sessions to the Building in Treasures (BIT) Workshop as an intervention to help improve symptoms of hoarding disorder. Project is funded by the Department of Psychiatry and Behavioral Sciences of Stanford University and the National Institute of Health.
- Serve as the primary contact with research participants, sponsors, and regulatory agencies.
- Perform clerical duties in the preparation of regulatory monitoring, inspections, and audits. Maintain all forms and documents, including consent forms and master subject logs.
- Collect and manage patient and laboratory data for research. Maintain research project databases, develop flow sheets, and complete study documents/case report forms.
- Assist with screening, recruiting, and obtaining consent of study participants. Schedule and/or call subjects for appointments; contact participants with reminders or other requirements. Review medical records and/or perform telephone or in-person interviews to gather data, as needed.
- Process study compensation payments and thank you letters to subjects upon completion of trial activities. Assist with post-study activities, as needed.
- Determine effective strategies for promoting and recruiting research participants and retaining participants in long-term clinical trials.
Brianna Joycelyn Wright
Assistant Clinical Research Coordinator, Psych/Public Mental Health & Population Sciences
Current Role at Stanford Assistant Clinical Research Coordinator, Psych/Public Mental Health & Population Sciences