School of Medicine
Showing 101-150 of 444 Results
Professor of Radiology (Abdominal Imaging) at the Stanford University Medical Center
Current Research and Scholarly Interests Imaging of gastrointestinal tract cancer
Simulated learning environment
Maximilian Diehn, MD, PhD
Associate Professor of Radiation Oncology (Radiation Therapy)
Current Research and Scholarly Interests My laboratory focuses on two main areas: 1) cancer stem cell biology and 2) novel biomarkers for identifying the presence of malignant cells (diagnostic), predicting outcome (prognostic), and predicting response to therapy (predictive). Areas of study include cancers of the lung, breast, and gastrointestinal system. Clinically I specialize in the treatment of lung cancer and applications of stereotactic ablative radiotherapy and perform both prospective and retrospective clinical studies.
Frederick M. Dirbas, MD
Associate Professor of Surgery (General Surgery) at the Stanford University Medical Center
Current Research and Scholarly Interests My research interests are focused on minimizing the impact of breast cancer from a diagnostic and therapuetic standpoint. Breast MRI is a powerful tool to facilitate the screening for and staging of breast cancer, and can be valuable adjunct to guide breast surgery. Oncoplastic surgical techniques optimize cosmesis after breast cancer surgery. Accelerated radiotherapy after lumpectomy decreases radiotherapy treatment times from 6 weeks to just 1 to 5 days.
Vasu Divi, MD
Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) at the Stanford University Medical Center
Bio Dr. Vasu Divi specializes in the treatment of head and neck cancer, both as a cancer surgeon and a reconstructive surgeon. Dr. Divi has a special interest in high-risk and advanced skin cancers, oral cavity cancers, and osteoradionecrosis of the head and neck. He utilizes advanced 3D-modeling to customize reconstruction of the jaw following surgery for cancer or radiation injuries.
Associate Professor of Biology
Current Research and Scholarly Interests My lab is interested in the relationship between cell death and metabolism. Using techniques drawn from many disciplines my laboratory is investigating how perturbation of intracellular metabolic networks can result in novel forms of cell death, such as ferroptosis. We are interested in applying this knowledge to find new ways to treat diseases characterized by insufficient (e.g. cancer) or excessive (e.g. neurodegeneration) cell death.
Sarah S. Donaldson, MD
Catharine and Howard Avery Professor in the School of Medicine
Current Research and Scholarly Interests Combined Modality Treatment of Cancer
Late Effects of Treatment
Genetic Effects of Cancer
Pediatric Radiation Oncolgy
Radiotherapy for Benign Diseases
Max H. Stein Professor and Professor of Statistics and of Biomedical Data Science
Current Research and Scholarly Interests Research Interests:
Professor of Pathology and of Medicine (Immunology and Rheumatology)
Current Research and Scholarly Interests Dendritic cells, macrophages, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer, autoimmune disease, neurodegenerative disease and metabolic disease.
Alice C. Fan
Assistant Professor of Medicine (Oncology) and, by courtesy, of Urology at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Fan is a physician scientist who studies how turning off oncogenes (cancer genes) can cause tumor regression in preclinical and clinical translational studies. Based on her findings, she has initiated clinical trials studying how targeted therapies affect cancer signals in kidney cancer and low grade lymphoma. In the laboratory, she uses new nanotechnology strategies for tumor diagnosis and treatment to define biomarkers for personalized therapy.
C. Garrison Fathman
Professor of Medicine (Immunology and Rheumatology), Emeritus
Current Research and Scholarly Interests My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity. We have identified and characterized a gene (GRAIL) that seems to control regulatory T cell (Treg) responsiveness by inhibiting the Treg IL-2 receptor desensitization. We have characterized a gene (Deaf1) that plays a major role in peripheral tolerance in T1D. Using PBC gene expression, we have provisionally identified a signature of risk and progression in T1D.
Professor of Medicine (Endocrinology, Gerontology and Metabolism), Emeritus
Current Research and Scholarly Interests Studies of the role of the vitamin D receptor in the action of 1,25-dihydroxyvitamin D, the active vitamin D hormone. Current efforts are evaluating the vitamin D receptor in breast and prostate cancer, osteoporosis and rickets.
Burnet C. and Mildred Finley Wohlford Professor in the School of Humanities and Sciences
Current Research and Scholarly Interests Human genetic and cultural evolution, mathematical biology, demography of China
Dean W. Felsher
Professor of Medicine (Oncology) and of Pathology
Current Research and Scholarly Interests My laboratory investigates how oncogenes initiate and sustain tumorigenesis. I have developed model systems whereby I can conditionally activate oncogenes in normal human and mouse cells in tissue culture or in specific tissues of transgenic mice. In particular using the tetracycline regulatory system, I have generated a conditional model system for MYC-induced tumors. I have shown that cancers caused by the conditional over-expression of the MYC proto-oncogene regress with its inactivation.
Russell D. Fernald
Benjamin Scott Crocker Professor of Human Biology, Emeritus
Current Research and Scholarly Interests In the course of evolution,two of the strongest selective forces in nature,light and sex, have left their mark on living organisms. I am interested in how the development and function of the nervous system reflects these events. We use the reproductive system to understand how social behavior influences the main system of reproductive action controlled by a collection of cells in the brain containing gonodotropin releasing hormone(GnRH)
Professor of Radiology (Molecular Imaging Program at Stanford)
Current Research and Scholarly Interests My focus is image-guided drug and gene delivery and I am engaged in the design of imaging devices, molecularly-targeted imaging probes and engineered delivery vehicles, drawing upon my education in biology and imaging physics and more than 20 years of experience with the synthesis and labeling of therapeutic particles. My laboratory has unique resources for and substantial experience in synthetic chemistry and ultrasound, CT, MR and PET imaging.
Professor of Chemical and Systems Biology and of Biochemistry
Current Research and Scholarly Interests My lab has two main goals: to understand the regulation of mitosis and to understand the systems-level logic of simple signaling circuits. We often make use of Xenopus laevis oocytes, eggs, and cell-free extracts for both sorts of study. We also carry out single-cell fluorescence imaging studies on mammalian cell lines. Our experimental work is complemented by computational and theoretical studies aimed at understanding the design principles and recurring themes of regulatory circuits.
George D. Smith Professor in Molecular and Genetic Medicine and Professor of Pathology and of Genetics
Current Research and Scholarly Interests We study natural cellular mechanisms for adapting to genetic change. These include systems activated during normal development and those for detecting and responding to foreign or unwanted genetic activity. Underlying these studies are questions of how a cells can distinguish information as "self" versus "nonself" or "wanted" versus "unwanted".
George A. Fisher Jr.
Colleen Haas Chair in the School of Medicine
Current Research and Scholarly Interests Clinical expertise in GI cancers with research which emphasizes Phase I and II clinical trials of novel therapies but also includes translational studies including biomarkers, molecular imaging, tumor immunology and development of immunotherapeutic trials.
Paul Graham Fisher, MD
Beirne Family Professor of Pediatric Neuro-Oncology, Professor of Pediatrics and, by courtesy, of Neurosurgery and of Epidemiology and Population Health at SUMC
Current Research and Scholarly Interests Clinical neuro-oncology: My research explores the epidemiology, natural history, and disease patterns of brain tumors in childhood, as well as prospective clinical trials for treating these neoplasms. Research interests also include neurologic effects of cancer and its therapies, and childhood headaches.
Professor of Medicine (Oncology) and of Genetics and, by courtesy, of Pediatrics
Current Research and Scholarly Interests Mammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNAdamage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer.
Associate Professor of Biology
Current Research and Scholarly Interests We study the evolution of complex traits by developing new experimental and computational methods.
Our work brings together quantitative genetics, genomics, epigenetics, and evolutionary biology to achieve a deeper understanding of how genetic variation shapes the phenotypic diversity of life. Our main focus is on the evolution of gene expression, which is the primary fuel for natural selection. Our long-term goal is to be able to introduce complex traits into new species via genome editing.
Assistant Professor of Radiation Oncology (Radiation and Cancer Biology)
Current Research and Scholarly Interests Mechanisms of DNA double-strand break repair and chromosomal translocations
Donald Kennedy Chair in the School of Humanities and Sciences and Professor of Genetics
Current Research and Scholarly Interests The long term goal of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether reengineering chaperone networks can provide therapeutic strategies.
Margaret T. Fuller
Reed-Hodgson Professor in Human Biology and Professor of Genetics and of Obstetrics/Gynecology (Reproductive and Stem Cell Biology)
Current Research and Scholarly Interests Regulation of self-renewal, proliferation and differentiation in adult stem cell lineages. Developmental tumor suppressor mechanisms and regulation of the switch from proliferation to differentiation. Cell type specific transcription machinery and regulation of cell differentiation. Developmental regulation of cell cycle progression during male meiosis.
Stephen J. Galli, MD
The Mary Hewitt Loveless, M.D. Professor in the School of Medicine and Professor of Pathology and of Microbiology and Immunology
Current Research and Scholarly Interests The goals of Dr. Galli's laboratory are to understand the regulation of mast cell and basophil development and function, and to develop and use genetic approaches to elucidate the roles of these cells in health and disease. We study both the roles of mast cells, basophils, and IgE in normal physiology and host defense, e.g., in responses to parasites and in enhancing resistance to venoms, and also their roles in pathology, e.g., anaphylaxis, food allergy, and asthma, both in mice and humans.
Sanjiv Sam Gambhir, MD, PhD
Current Research and Scholarly Interests My laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the field of molecular imaging. Imaging for the purpose of better understanding cancer biology and applications in gene and cell therapy, as well as immunotherapy are all being studied. A key long-term focus is the earlier detection of cancer by combining in vitro diagnostics and molecular imaging.
Kristen N Ganjoo
Associate Professor of Medicine (Oncology) at the Stanford University Medical Center
Current Research and Scholarly Interests Giant cell tumor of the bone
Gastrointestinal stromal tumors
Soft tissue sarcoma
Younger Family Professor and Professor of Structural Biology
Current Research and Scholarly Interests Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology. We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.
Rehnborg Farquhar Professor
Current Research and Scholarly Interests The role of nutrition in individual and societal health, with particular interests in: plant-based diets, differential response to low-carb vs. low-fat weight loss diets by insulin resistance status, chronic disease prevention, randomized controlled trials, human nutrition, community based studies, Community Based Participatory Research, sustainable food movement (animal rights and welfare, global warming, human labor practices), stealth health, nutrition policy, nutrition guidelines
Assistant Professor (Research) of Medicine (Biomedical Informatics) and, by courtesy, of Biomedical Data Science
Current Research and Scholarly Interests Computational systems biology of human disease. Particular focus on integration of high-throughput datasets with each other, and with phenotypic information and clinical outcomes.
Assistant Professor of Medicine (Biomedical Informatics) and of Biomedical Data Science
Current Research and Scholarly Interests My lab focuses on biomedical data fusion: the development of machine learning methods for biomedical decision support using multi-scale biomedical data. We primarily use methods based on regularized linear regression to accomplish this. We primarily focus on applications in oncology and neuroscience.
Amato J. Giaccia
Jack, Lulu and Sam Willson Professor, Professor of Radiation Oncology, Emeritus
Current Research and Scholarly Interests During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically.
Iris C. Gibbs, MD, FACR, FASTRO
Professor of Radiation Oncology (Radiation Therapy) and, by courtesy, of Neurosurgery at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Gibbs is a board-certified radiation oncologist who specializes in the treatment of CNS tumors. Her research focuses on developing new radiation techniques to manage brain and spinal tumors in adults and children. Dr. Gibbs has gained worldwide acclaim for her expertise in Cyberknife robotic radiosurgery.
Kathryn Simmons Stamey Professor
Current Research and Scholarly Interests Benign Prostatic Hyperplasia- Evaluation and development of new minimally invasive techniques
Endourology: developing, designing and evaluating new instruments
Bladder cancer: outcomes of treatment
BPH: cryotherapy and HIFU
Professor of Radiology (Radiological Sciences Lab) and, by courtesy, of Psychology and of Electrical Engineering
Current Research and Scholarly Interests My present research is devoted to the advancement of functional magnetic resonance imaging sciences for applications in basic understanding of the brain in health and disease. We collaborate closely with departmental clinicians and with others in the school of medicine, humanities, and the engineering sciences.
Professor of Epidemiology and Population Health and of Medicine (Primary Care and Population Health)
Current Research and Scholarly Interests I am interested in issues relating to the representation and measurement of evidence in medical research, and determinants of the truth of medical findings, using a Bayesian framework. I also do work in evidence synthesis, comparative effectiveness research, and the ethics of clinical research.
Professor of Medicine (Hematology) at the Stanford University Medical Center
Current Research and Scholarly Interests My research interests include phase I/II clinical trial evaluation of novel therapies for the following diseases:
--Myelodysplastic syndromes (MDS)
--Chronic myelogenous leukemia (CML)
--Acute myelogenous leukemia (AML)
--Myeloproliferative disorders (MPDs) including:
Dr. Morris Herzstein Professor of Biology
Current Research and Scholarly Interests We study the molecular mechanisms by which chromatin-signaling networks effect nuclear and epigenetic programs, and how dysregulation of these pathways leads to disease. Our work centers on the biology of lysine methylation, a principal chromatin-regulatory mechanism that directs epigenetic processes. We study how lysine methylation events are generated, sensed, and transduced, and how these chemical marks integrate with other nuclear signaling systems to govern diverse cellular functions.
Gerald Grant, MD, FACS
Endowed Professor in Pediatric Neurosurgery, Botha Chan Endowed Professor and Professor, by courtesy, of Neurology at the Stanford University Medical Center
Current Research and Scholarly Interests Dr. Grant directs a Blood-brain Barrier Translational Laboratory focusing on enhancing drug delivery to brain tumors in children.
Associate Professor of Pathology at the Stanford University Medical Center
Current Research and Scholarly Interests I have research interests in the interaction of hematolymphoid neoplasia with the microenvironment. For example, I use a combination of immunohistochemistry, immunofluorescence and image analysis techniques to evaluate the mesenchymal stromal cell compartment in myelodysplastic syndrome (pre-leukemic bone marrow failure disorder). I also have interests in lymphoma vasculature and the tropism of lymphoma for specific types of vasculature.
Associate Professor of Radiation Oncology (Radiation Physics) and, by courtesy, of Radiology (Molecular Imaging Program at Stanford)
Current Research and Scholarly Interests Applications of molecular imaging in radiation therapy, development of hypoxia and radiosensitivity imaging techniques, small animal image-guided conformal radiotherapy, image processing and analysis.
Henry T. (Hank) Greely
Deane F. and Kate Edelman Johnson Professor of Law and, Professor, by courtesy, of Genetics
Current Research and Scholarly Interests Since 1992 my work has concentrated on ethical, legal, and social issues in the biosciences. I am particularly active on issues arising from neuroscience, human genetics, and stem cell research, with cross-cutting interests in human research protections, human biological enhancement, and the future of human reproduction.
Harry B Greenberg
The Joseph D. Grant Professor in the School of Medicine and Professor of Microbiology and Immunology
Current Research and Scholarly Interests Molecular mechanisms of pathogenesis; determinants of protective immunity; host range and tissue tropism in liver and GI tract pathogenic viruses and studies of vaccines in people.