School of Medicine
Showing 1-20 of 825 Results
Alistair Aaronson, MD
Clinical Instructor, Medicine - General Medical Disciplines
Current Research and Scholarly Interests Quality Improvement, Clinical Documentation Improvement, Post-op Complication Reduction, Microgravity-induced and Disuse Osteoporosis
Oscar J. Abilez
Instructor, Medicine - Cardiovascular Medicine
Current Research and Scholarly Interests Bioengineering, biophysical control of cardiovascular development, pluripotent stem cell biology, optogenetics, electrophysiology, cell mechanics, directed cellular evolution, multiscale engineering, microfluidics, computational biology
Saul A. Rosenberg, MD, Professor of Lymphoma
Current Research and Scholarly Interests Clinical investigation in Hodgkin's disease, non-Hodgkin's Lymphomas and cutaneous lymphomas. Experimental therapeutics with novel chemotherapy and biologically targeted therapies.
The research program is highly collaborative with radiation oncology, industry, pathology and dermatology.
Sumbul Ahmad Desai
Clinical Assistant Professor, Medicine - General Medical Disciplines
Current Research and Scholarly Interests Intersection of Media and Medicine, Cost Effective Healthcare, The effect of media on the geriatric population
Clinical Associate Professor, Medicine - General Medical Disciplines
Current Research and Scholarly Interests Medical education research; Intergenerational teaching/learning; Analysis of effects of duty hour regulations on housestaff training and ways to improve the system
Ash A. Alizadeh, MD/PhD
Assistant Professor of Medicine (Oncology)
Current Research and Scholarly Interests My research is focused on attaining a better understanding of the initiation, maintenance, and progression of tumors, and their response to current therapies toward improving future treatment strategies. In this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.
Clinically, I specialize in the care of patients with lymphomas, working on translating our findings in prospective cancer clinical trials.
Instructor, Medicine - Oncology
Current Research and Scholarly Interests I am interested in identifying targeted therapies for triple-negative breast cancers and developing a novel strategy of biomarker-based chemoprevention for hereditary cancers that arise due to mutations in the Breast Cancer Susceptibility Gene 1 (BRCA1).
Russ B. Altman
Kenneth Fong Professor and Professor of Bioengineering, of Genetics, of Medicine (General Medical Discipline) and, by courtesy, of Computer Science
Current Research and Scholarly Interests I refer you to my web page for detailed list of interests, projects and publications. In addition to pressing the link here, you can search "Russ Altman" on http://www.google.com/
Maite Alvarez Rodriguez
Postdoctoral Research fellow, Bone Marrow Transplantation
Current Research and Scholarly Interests Cancer immunobiology and the development of immunological treatments against tumorigenesis/cancer.
Natural Killer (NK) cell-based immunotherapies and NK biology.
Hematopoietic stem cell transplanation
Instructor, Medicine - Nephrology
Current Research and Scholarly Interests ESRD and physical activity
ESRD and vitamin D deficiency
Management of CKD and ESRD in developing regions
Assistant Professor of Medicine (Infectious Diseases)
Current Research and Scholarly Interests Our laboratory aims to develop innovative approaches to the control of infectious diseases in resource-limited settings. Drawing upon the fields of epidemiology, microbiology and engineering, we strive to find solutions to extend the technologies that underlie diagnosis and treatment of infectious diseases to "last-mile" communities.
Justin P. Annes M.D., Ph.D.
Assistant Professor of Medicine (Endocrinology)
Current Research and Scholarly Interests The ANNES LABORATORY of Molecular Endocrinology: Leveraging Chemical Biology to Treat Endocrine Disorders
The prevalence of diabetes is increasing at a staggering rate. By the year 2050 an astounding 25% of Americans will be diabetic. The goal of my research is to uncover therapeutic strategies to stymie the ensuing diabetes epidemic. To achieve this goal we have developed a variety of innovate experimental approaches to uncover novel approaches to curing diabetes.
(1) Beta-Cell Regeneration: Diabetes results from either an absolute or relative deficiency in insulin production. Our therapeutic strategy is to stimulate the regeneration of insulin-producing beta-cells to enhance an individual’s insulin secretion capacity. We have developed a unique high-throughput chemical screening platform which we use to identify small molecules that promote beta-cell growth. This work has led to the identification of key molecular pathways (therapeutic targets) and candidate drugs that promote the growth and regeneration of islet beta-cells. Our goal is to utilize these discoveries to treat and prevent diabetes.
(2) The Metabolic Syndrome: A major cause of the diabetes epidemic is the rise in obesity which leads to a cluster of diabetes- and cardiovascular disease-related metabolic abnormalities that shorten life expectancy. These physiologic aberrations are collectively termed the Metabolic Syndrome (MS). My laboratory has developed an original in vivo screening platform t to identify novel hormones that influence the behaviors (excess caloric consumption, deficient exercise and disrupted sleep-wake cycles) and the metabolic abnormalities caused by obesity. We aim to manipulate these hormone levels to prevent the development and detrimental consequences of the MS.
HEREDIATY PARAGAGLIOMA SYNDROME
The Hereditary Paraganglioma Syndrome (hPGL) is a rare genetic cancer syndrome that is most commonly caused by a defect in mitochondrial metabolism. Our goal is to understand how altered cellular metabolism leads to the development of cancer. Although hPGL is uncommon, it serves as an excellent model for the abnormal metabolic behavior displayed by nearly all cancers. Our goal is to develop novel therapeutic strategies that target the abnormal behavior of cancer cells. In the laboratory we have developed hPGL mouse models and use high throughput chemical screening to identify the therapeutic susceptibilities that result from the abnormal metabolic behavior of cancer cells.
As a physician scientist trained in clinical genetics I have developed expertise in hereditary endocrine disorders and devoted my efforts to treating families affected by the hPGL syndrome. By leveraging our laboratory expertise in the hPGL syndrome, our care for individuals who have inherited the hPGL syndrome is at the forefront of medicine. Our goal is to translate our laboratory discoveries to the treatment of affected families.