School of Medicine
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Associate Professor of Pediatrics (Cancer Biology)
Current Research and Scholarly Interests Genome Editing and Population Dynamics for Gene Therapy and Cancer Research
Associate Professor of Pediatrics (Cancer Biology) and of Genetics
Current Research and Scholarly Interests We are interested in the links between the basic cell cycle machinery and the factors controlling self-renewal, differentiation, and regeneration. In particular, we are intrigued by the differences and the similarities between "normal" cells, cancer cells, and stem cells. We investigate the mechanisms by which normal cells become tumor cells, and we aim to understand the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells.
Associate Professor (Research) of Pediatrics (Cancer Biology)
Current Research and Scholarly Interests Our laboratory is devoted to the analysis of pathways involved in the initiation, progression, and maintenance of cancer. Utilizing the mouse as a model system, we strive to understand aberrant oncogenic signaling, the role of the tumor microenvironment and the mechanisms involved in chemotherapy response and resistance at the molecular, cellular, and organismal levels.