School of Medicine


Showing 1-10 of 15 Results

  • Calvin Kuo

    Calvin Kuo

    Professor of Medicine (Hematology) and, by courtesy, of Chemical and Systems Biology

    Current Research and Scholarly Interests We explore angiogenesis, cancer genomics, intestinal stem cells, and hepatic glucose metabolism. Angiogenesis projects include endothelial miRNA and GPCR ko mice, blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy. Intestinal stem cell projects use primary intestinal culture and mouse genetics to study injury-inducible vs homeostatic stem cells. We use primary organoid cultures of diverse tissues for oncogene functional screening and therapeutics discovery.

  • Joseph (Joe) Lipsick

    Joseph (Joe) Lipsick

    Professor of Pathology, Genetics and, by courtesy, of Biology

    Current Research and Scholarly Interests Function and evolution of the Myb oncogene family; function and evolution of E2F transcriptional regulators and RB tumor suppressors; epigenetic regulation of chromatin and chromosomes; cancer genetics.

  • Maxence Nachury

    Maxence Nachury

    Assistant Professor of Molecular and Cellular Physiology

    Current Research and Scholarly Interests We study the primary cilium, a once-obscure cellular organelle recently "re-discovered" for its role in a number of signaling pathways. Defects in cilium biogenesis lead to a variety of hereditary disorders characterized by retinal degeneration, kidney cysts and obesity. Our goal is to characterize these disorders at the molecular and cellular levels to gain insight into the basic mechanisms of primary cilium biogenesis and to discover novel ciliary signaling pathways.

  • William Nelson

    William Nelson

    Rudy J. and Daphne Donohue Munzer Professor in the School of Medicine and Professor of Molecular and Cellular Physiology

    Current Research and Scholarly Interests Our research objectives are to understand the cellular mechanisms involved in the development and maintenance of epithelial cell polarity. Polarized epithelial cells play fundamental roles in the ontogeny and function of a variety of tissues and organs.

  • Anthony Oro  MD/PhD

    Anthony Oro MD/PhD

    Professor of Dermatology

    Current Research and Scholarly Interests Our lab uses the skin to answer questions about epithelial stem cell biology, differentiation and carcinogenesis using genomics, genetics, and cell biological techniques. We have studied how hedgehog signaling regulates regeneration and skin cancer, and how tumors evolve to develop resistance. We study the mechanisms of early human skin development using human embryonic stem cells. These fundamentals studies provide a greater understanding of epithelial biology and novel disease therapeutics.

  • Suzanne Pfeffer

    Suzanne Pfeffer

    Emma Pfeiffer Merner Professor in the Medical Sciences

    Current Research and Scholarly Interests The goal of our research is to elucidate the molecular mechanisms by which proteins are targeted to specific membrane compartments. How do transport vesicles select their contents, bud, translocate through the cytoplasm, and then fuse with their targets? We study the Ras-like Rab GTPases--how they serve as master regulators of all receptor trafficking events. We also study how cells acquire cholesterol from the diet and from LDL.

  • Julien Sage

    Julien Sage

    Associate Professor of Pediatrics (Cancer Biology) and of Genetics

    Current Research and Scholarly Interests We are interested in the links between the basic cell cycle machinery and the factors controlling self-renewal, differentiation, and regeneration. In particular, we are intrigued by the differences and the similarities between "normal" cells, cancer cells, and stem cells. We investigate the mechanisms by which normal cells become tumor cells, and we aim to understand the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells.

  • Michael Snyder

    Michael Snyder

    Stanford W. Ascherman, MD, FACS, Professor in Genetics

    Current Research and Scholarly Interests Our laboratory use different omics approaches to study a) regulatory networks, b) intra- and inter-species variation which differs primarily at the level of regulatory information c) human health and disease. For the later we have established integrated Personal Omics Profiling (iPOP), an analysis that combines longitudinal analyses of genomic, transcriptomic, proteomic, metabolomic, DNA methylation, microbiome and autoantibody profiles to monitor healthy and disease states

  • Aaron Straight

    Aaron Straight

    Associate Professor of Biochemistry

    Current Research and Scholarly Interests We study the process of cell division. Our research is focused on understanding how chromosomes are segregated during mitosis and how cells divide during cytokinesis.

  • Zijie Sun

    Zijie Sun

    Associate Professor of Urology and of Genetics

    Current Research and Scholarly Interests We focus on understanding the molecular mechanism of transcription factors that govern the transformation of normal cells to a neoplastic state. We are especially interested in nuclear hormone action and its interactions with other signaling pathways in tumor development and progression.

Stanford Medicine Resources: