School of Medicine
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Instructor, Pediatrics - Gastroenterology
Bio I am a pediatric physician-scientist striving to advance cystic fibrosis clinical care and translational research. Clinically, I am focused on gastrointestinal manifestations of cystic fibrosis, developing diagnostic and therapeutic modalities to improve the gastrointestinal and liver health of those with cystic fibrosis. I also specialize in the clinical management of pediatric pancreatitis and am involved with the international INSPPIRE consortium to study pediatric pancreatitis. In the laboratory, my projects are centered around understanding mechanisms of ion transport in cystic fibrosis tissues and determining how loss of CFTR ion transport leads to pathologic changes in human physiology. Our laboratory has specialized expertise in the measurement of bicarbonate transport. We are also part of a Multi-PI collaboration pursuing CFTR gene editing and stem cell engraftment for the treatment of cystic fibrosis.
Eric Sibley, M.D., Ph.D.
Professor of Pediatrics (Gastroenterology)
Current Research and Scholarly Interests Genetic Regulation of Intestinal Development and Maturation. We study transcriptional mechanisms regulating the spatial and temporal restriction of intestine-specific gene expression during gut development. Our approach is to characterize the function of gene-specific DNA cis elements and interacting nuclear proteins in cell culture and in transgenic animals. The goal is to relate the gene-specific control mechanisms to the broader pathways specifying acquisition of a small intestinal phenotype.