School of Medicine
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Instructor, Cardiovascular Institute
Current Research and Scholarly Interests Heart failure is a major cause of death worldwide. Up to 50% of these heart failure patients die from arrhythmias and sudden cardiac death (SCD). An intriguing aspect of SCD, however, is that affected individuals exhibit varied susceptibility to arrhythmogenic events, making risk stratification and prevention challenging. The overarching goal of Dr. Rojas-Muñoz's research is to uncover new molecular mediators of disease and use this information to develop novel diagnostic and therapeutic modalities for SCD. Human-induced Pluripotent Stem Cells-derived Cardiomyocytes (hiPSC-CMs) offers an unprecedented opportunity to model arrhythmia mechanisms and link them to disease susceptibility and disease progression. Therefore, Dr. Rojas-Muñoz's current approach leverages the use hiPSC-CMs to define the molecular components that mediate the alteration of cardiac currents upon cardiomyocyte stress and test for their ability to alter disease manifestation in patient specific models of long QT syndrome (LQTS) and in animal models of arrhythmia. Results from Dr. Rojas-Muñoz's research will provide a clearer picture of the circuit inducing and maintaining lethal arrhythmias, potentially leading to new strategies to lower morbidity and mortality of individuals at risk of SCD.
Professor of Pediatrics (Pediatric Cardiology) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests Research interests include the study of Heart Failure, Cardiomyopathy and ventricular dysfunction in children, from a clinical perspective. Investigations include clinical trials of medications, cardiac resynchronization, and mechanical circulatory support.
Elsie Gyang Ross
Assistant Professor of Surgery (Vascular Surgery) and of Medicine (BMIR) at the Stanford University Medical Center
Bio Dr. Ross is a vascular surgeon and research scientist. She graduated from Stanford University School of Medicine in 2011 and completed her vascular surgery 0+5 residency at Stanford University School of Medicine in 2018. During her residency, she completed a two-year post-doctoral fellowship in biomedical informatics. Her current research focuses on using machine learning and electronic health records for early disease identification, precision medicine, and evaluating opportunities to engage in patient education beyond the clinic.
Stephen J. Roth
Professor of Pediatrics (Cardiology) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests Randomized Therapeutic Trials in Pediatric Heart Disease, NIH/U01 GrantNo. HL68285 2001-2006.
Heparin and the Reduction of Thrombosis (HART) Study. Pediatric Health Research Fund Award, Stanford Univ Sch of Medicine, 2005-2006.
A Pilot Trial fo B-type Natriuretic Peptide for Promotion of Urine Output in Diuretic-Resistant Infants Following Cardiovascular Surgery.Pediatric Health Research Fund Award, Stanford Univ Sch of Medicine, 2005-2006.