School of Medicine
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Associate Professor (Research) of Radiation Oncology (Radiation and Cancer Biology), of Radiology (Molecular Imaging Program at Stanford) and, by courtesy, of Medicine (Oncology)
Current Research and Scholarly Interests My research interests focus on the design and discovery of synthetic, and natural product inspired small molecules which can be used as probes for developing understanding of biological phenomena, including protein-protein interactions and modulation of signal transduction pathways. My laboratory employs the tools of synthetic medicinal chemistry, molecular modeling and chemical biology for translational research in drug discovery, development, imaging and radiation.
Suleiman Alfred Massarweh
Current Research and Scholarly Interests My work is focused in investigating mechanisms of endocrine resistance in ER-positive breast cancer and novel clinical trial designs of combined ER and targeted therapeutics. Primary areas of investigation are in metastatic disease and preoperative clinical trials.
Additional areas of interest include breast cancer in young women, in men, and breast cancer diagnosed during pregnancy.
Professor of Microbiology and Immunology
Current Research and Scholarly Interests 1. Improvement of our newly discovered cancer prodrug regimen that permits noninvaisve visualization of drug activation. 2. Tracking tumors & cancer metastases using bacterial magnetite and newly developed single-cell tracking by MRI. 3. Molecular basis of bacterial planktonic and biofilm antibiotic resistance on Earth and under space microgravity -- development of new countermeasures; 4. Bioremediation.
The George D. Smith Professor in Translational Medicine
Current Research and Scholarly Interests Two areas: 1. Using rationally-designed peptide inhibitors to study protein-protein interactions in cell signaling. Focus: protein kinase C in heart and large GTPases regulating mitochondrial dynamics in neurodegdenration. 2. Using small molecules (identified in a high throughput screens and synthetic chemistry) as activators and inhibitors of aldehyde dehydrogenases, a family of detoxifying enzymes, and glucose-6-phoshate dehydrogenase, in normal cells and in models of human diseases.
Prithvi Mruthyunjaya, MD, MHS
Associate Professor of Ophthalmology at the Stanford University Medical Center
Current Research and Scholarly Interests Dr Mruthyunjaya has maintained a broad research interest with publications in both ocular oncology and retinal diseases.
His focus is on multi-modal imaging of ocular tumors and understanding imaging clues that may predict vision loss after ocular radiation therapy. He coordinates multi-center research on the role of genetic testing and outcomes of treatments of ocular melanoma.
In the field of retinal diseases, his interests are in intra-operative imaging to enhance surgical accuracy.