School of Medicine
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Katherine Kaplan
Clinical Instructor, Psychiatry and Behavioral Sciences
Current Research and Scholarly Interests Dr. Kaplan's research interests span four (often overlapping) domains: (1) pathophysiologic aspects of insomnia and hypersomnia in mood disorders, including mechanisms, correlates, and sequelae of these sleep disturbances; (2) behavioral interventions for sleep disturbances in adults and adolescents; (3) circadian and psychosocial factors impacting sleep in adolescence; and (4) machine learning approaches to big data.
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Debra Karhson
NX - Professional - Research, Psychiatry and Behavioral Sciences - Child and Adolescent Psychiatry and Child Development
Bio I am interested in understanding the neural mechanisms that underlie cognitive and social functioning heterogeneity in autism spectrum disorder (ASD). Impairments in social and cognitive functioning in children with ASD are intrinsically related to the changes in information processing. Moreover, social and cognitive functioning are emergent neural processes that can be manipulated by robust molecular neuromodulators. Social behaviors are specifically related to the neuropeptides, oxytocin (OT) and arginine vasopressin (AVP), while both social and cognitive functioning have been related to the endogenous cannabinoid (or endocannabinoid) system. Therefore, my postdoctoral research (funded by a T32 postdoctoral fellowship from the NIMH) investigates the role of neuromodulators (i.e., social neuropeptides and endocannabinoids) in social functioning in autistic children. My PI-lead efforts are include mass spectrometry method development and treatment-related clinical neurophysiological assessment in autistic children. Individually, my research interests are centered on leveraging a translational neuroscience skill set to interrogate information processing in ASD pathophysiology and understand its relationship with (potential dysregulation of) endocannabinoid signaling.
