School of Medicine
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David M Garcia
Postdoctoral Research Fellow, Chemical and Systems Biology
Bio I received a B.S. in Biochemistry and Molecular Biology from UC Santa Cruz, with one year of my bachelor's spent at the Pontifical Catholic University of Chile. Returning to the Bay Area where I grew up, I worked briefly at the VA Medical Center, San Francisco. I then did my Ph.D. studies at MIT, in David Bartel’s lab at the Whitehead Institute. I discovered new features of microRNA recognition sequences that were so predictive of mRNA repression that they were integrated into a major update of TargetScan.org, a microRNA target prediction program that receives ~20,000 visitors per month. I became interested in the link between protein homeostasis and RNA regulation, and joined Dan Jarosz’s lab at Stanford to study novel prion-like states of RNA binding proteins. My interest in prions also led me to a collaboration with Jon Clardy of Harvard, in which we identified for the first time an example of a bacterially secreted molecule that potently induces a prion. I continue to be fascinated with the biologically beneficial roles of prions, how they are induced in nature and the resulting physiological consequences, as well as their characteristic molecular features. In addition to research, I have longstanding interests in science communication for the public (see publications) and celebrating diversity in the academy through outreach opportunities.
I will be starting my own group at the University of Oregon, in the Institute of Molecular Biology, in December 2018. Please visit garcialab.org