School of Medicine
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Postdoctoral Research Fellow, Psychiatry
Current Research and Scholarly Interests I have been venturing the career of characterizing insulin resistance genes, as the underlying risk factor of type 2 diabetes and metabolic syndrome. My earlier postdoctoral fellowship at the Department of Cardiovascular Medicine involved the functional genomic of diabetes and glycemic traits loci by using deep phenotyping approach i.e., multi-OMICs and transgenic mice.
At my current research, I am harnessing the epigenomic analysis in the global birth cohorts. I aim to unravel the origin of insulin resistance in the etiology of diabetes, mild cognitive impairment, and Alzheimer's diseases. Certain ethnicities develop insulin resistance and diabetes even with the normal weight and at younger ages. Therefore, it is essential to distinguish genes that predispose high-risk individuals to insulin resistance in the presence or absence (lipodystrophy) of obesity.
The main plan of my research is to expand follow-up studies on the global birth cohorts from diverse ethnic groups to eventually enable precise screening. This aim is aligned with the missions of Stanford Long-Range Planning and Precision Health to diminish health disparities. Therefore, our research supports the University mission of deep phenotyping and care of diverse patients and populations. These studies have the potential to specify mechanistic and causality insights from the drivers of diabetes and insulin resistance risk in different ethnicities. The ultimate goal of my research is to pave the way for opportunities to prevent insulin resistance as early as 10-20 years before the onset of diabetes and the age-related adverse outcomes such as vascular dementia and to reduce the widening ethnic inequalities.
My overall goal is to promote the field of global precision medicine with an eye toward the minority and under-represented communities in genomic medicine.
William O Faustman
Clinical Professor (Affiliated) [Vapahcs], Psychiatry and Behavioral Sciences
Bio Dr. Faustman received his doctorate in clinical psychology from the University of Mississippi and completed his internship at the VA Palo Alto Health Care System. He has an active interest in training, administration, forensic practice, and clinical care in inpatient psychiatry. His research interests have focused on severe mental illness with an emphasis in areas such as cognition and clinical assessment.. He serves as a member of the Stanford IRB and coordinates the American Psychological Association accredited postdoctoral fellowship program at the VA Palo Alto. He holds Chartered Psychologist status with the British Psychological Society,
Professor of Psychiatry and Behavioral Sciences at the Stanford University Medical Center, Emeritus
Current Research and Scholarly Interests Autism and Asperger's Disorder.
Genetically-based neurodevelopmental disorder, including Velocardiofacial Syndrome, Smith-Magenis Syndrome, Williams Syndrome, and Fragile X Syndrome.
Intellectual Disability (mental retardation) and psychiatric disorders.
Developmental Language Disorder and Learning Disabilities.
Sensory impairment in children, including visual and hearing impairment.
Psychiatric aspects of medical illness and disability in children.
Howard H Fenn MD
Clinical Associate Professor (Affiliated) [Vapahcs], Psychiatry and Behavioral Sciences
Inpatient psychiatry attending at VA HCS Palo Alto for over 30 years.
Medical Director, Geriatric Psychiatry unit, VA HCSC Palo Alto/Menlo Park for 10 years
Outpatient psychiatrist at Palo Alto Medical foundation/Sutter for 15 years
Consultation practice on legal issues and court testimony for >40 years
Expert consultant/witness for Coleman vs. California Department of Corrections for 4 years
Qualified Medical Examiner (QME) for Division of Worker's Compensation for 15 years
Compensation and Pension Unit, VA HCS Palo Alto for 5 years
Psychiatric Issues in Cognitive Impairment -- Stanford/VA Alzheimer's Center (SVAAC)
Legal Aspects of Geriatric Psychiatry (Stanford/VA Geriatric Psychiatry Fellowship
Didactic topics on inpatient psychiatry rotation for Stanford Geriatric Psychiatry fellows
Program Director, Stanford/VA Geriatric Psychiatry Fellowship, 3 years
Site Director, Inpatient Psychiatry Rotation/Geriatric Medicine Fellowship --6 years
Lead Editor of textbook, Inpatient Geriatric Psychiatry, published by Springer in 2019.
Slide presentations published by the American Society of Clinical Pharmacology (ASCP), editor Ira Glick, MD, entitled:
--Pharmacological Treatment of PTSD
--Behavioral and Psychological symptoms of Dementia
Chapters, review articles on topics of Medication management for Major Neurocognitive Disorder with Behavioral Disturbance
Chapter in Inpatient Geriatric Psychiatry, in On-Call Geriatric Psychiatry (2016), Springer.
Lief Ericsson Fenno
Instructor, Psychiatry and Behavioral Sciences
Bio Dr. Fenno is a psychiatrist and Instructor at Stanford University School of Medicine.
Leveraging his strengths in neuroscience research and bioengineering, his goal is to design, construct, validate, and apply novel molecular and viral tools to understand the brain in health and disease for the benefit of diverse patient populations. His clinical interests include the treatment of substance use disorders and co-occurring mood disorders.
His specific research interests include the development and application of novel optogenetic tools that combine genetically encoded molecules and light to modulate neurons. Dr. Fenno directs a team focused on expanding the use of novel, intersectional viral targeting approaches, with the objective of precisely establishing links between neuron circuitry and behavior. He has patented advances for optically controlled CNS dysfunction and social dysfunction.
Dr. Fenno has co-written articles on optogenetic tools and other topics in the journals Annual Review of Neuroscience, Neurobiology of Mental Illness, Molecular Psychiatry, Current Protocols in Neuroscience, Nature, and Cell. He is also the co-author of articles on neural mechanisms of autism spectrum disorder, which have appeared in Science Translational Medicine and Nature.
Dr. Fenno has delivered presentations worldwide at events including the meeting of the National Science Foundation NeuroNex Program of Next Generation Networks for Neuroscience. He also has been an invited speaker at the Robarts Research Institute, a Canada-based facility accelerating medical discovery of treatments for some of the most debilitating diseases of our time, and the Gordon Research Conference on Molecular Pharmacology, an international forum for the presentation of pre-publication frontier research.
For his scholarship and teaching achievements, Dr. Fenno has won numerous honors. They include the Laughlin Fellowship from the American College of Psychiatrists, which honors individuals deemed likely to make a significant contribution to the field of psychiatry, and the Humanism and Excellence in Teaching Award from the Arnold P. Gold Foundation, which honors exceptional teaching skills and commitment to the compassionate treatment of patients and families, students, and colleagues.
Dr. Fenno is a member of the Society for Neuroscience, The American Medical Association, and the American Society of Addiction Medicine.