School of Medicine
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Postdoctoral Research Fellow, Cardiovascular Medicine
Current Research and Scholarly Interests Here at Stanford cardiovascular medicine, I have been pursuing the career of characterizing cardiometabolic disease genes by joining my current advisors who co-lead international consortium on Genome-Wide Association Studies (GWAS) of insulin resistance (GENESIS) as the underlying risk factor of type 2 diabetes and metabolic syndrome. Currently, we are scrutinizing the post-genomic studies of diabetes and glycemic traits associated loci by means of deep phenotyping approach i.e. multi-OMICs. I am, in particular, eager to harness these technologies to unravel the underlying cause of diabetes and the development of insulin resistance in the presence or absence (lipodystrophy) of obesity.
Here are two examples of our current theme of research we are following:
- Demonstrate FAM13A as the causative gene linking fasting insulin level and body fat distribution.
- Defined pathophysiological link of Human NAT2 and mouse orthologue, Nat1, to mitochondria function and cardiometabolic risk.