School of Medicine

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  • Theodore Fainstat

    Theodore Fainstat

    Professor of Obstetrics and Gynecology, Emeritus

    Current Research and Scholarly Interests Gynecologic and obstetric infections.

  • Linda Giudice

    Linda Giudice

    Stanley McCormick Memorial Professor in the School of Medicine, Emeritus

    Current Research and Scholarly Interests Our research is in reproductive endocrinology and reproductive genomics. It focuses on human endometrial biology as it relates to basic biological mechanisms underlying steroid hormone action in this tissue, normal and abnormal placenta-decidua interactions, mechanisms underlying placentation and abnormal fetal growth, endometrial stem cells, and functional genomics for diagnostics and therapeutics of endometrial disorders. We also study mechanisms underlying ovarian follicle steroidogenesis.

  • Wm. LeRoy Heinrichs

    Wm. LeRoy Heinrichs

    Professor of Obstetrics and Gynecology, Emeritus

    Current Research and Scholarly Interests Surgical simulation; team-training in virtual environments; online training of healthcare providers in virtual environments; tele-medicine for acute & chronic disease management in virtual environments

  • Nihar Nayak, Ph.D., D.V.M.

    Nihar Nayak, Ph.D., D.V.M.

    Associate Professor (Research) of Obstetrics and Gynecology

    Current Research and Scholarly Interests Research in my laboratory is focused on understanding the mechanisms of endometrial angiogenesis and vascular remodeling during the menstrual cycle and pregnancy. We are particularly interested in understanding the mechanisms of spiral artery growth and remodeling in the primate uterus. These arteries are unique to the primate endometrium. They develop from the radial arteries of the myometrium and course through the endometrium, where they develop their coiled structure and vascularize primarily the upper endometrial zones. Their growth is primarily driven by progesterone in the luteal phase of the menstrual cycle and pregnancy. At the end of a nonfertile cycle, when progesterone levels fall, the spiral arteries severely constrict, leading to ischemia of the upper endometrial zones and menstrual breakdown of endometrium. During pregnancy, the trophoblasts invade the spiral arteries and replace the internal lining of these arteries, thereby regulate the vascular resistance and blood flow to the placenta and fetus. The degree of trophoblast invasion into these arteries appears to be a major determinant of pregnancy outcome. Inadequate invasion, particularly restricted endovascular invasion of spiral arteries, has been implicated in the pathophysiology of preeclampsia, preterm labor, and intrauterine growth restriction (lUGR). We believe that most of the pregnancy-related vascular complications manifested late in gestation, including preeclampsia, have their origins early in pregnancy. Our main goal is to identify the abnormalities in implantation that may lead to various pregnancy-related vascular complications.

  • Mary Polan

    Mary Polan

    Katharine Dexter McCormick and Stanley McCormick Memorial Professor in the School of Medicine, Emerita

    Current Research and Scholarly Interests Dr. Polan's research has centered around ovarian function during both the follicular and luteal phases. Studies of steroidogenesis, LH receptor synthesis, and the involvement of the plasminogen activator system in ovarian events have been performed.

  • Natalie L. Rasgon

    Natalie L. Rasgon

    Professor of Psychiatry and Behavioral Sciences, and, by courtesy, of Obstetrics and Gynecology at the Stanford University Medical Center

    Current Research and Scholarly Interests Dr. Rasgon has been involved in longitudinal placebo-controlled neuroendocrine studies for nearly two decades, and she has been involved in neuroendocrine and brain imaging studies of estrogen effects on depressed menopausal women for the last eight years. It should be noted that in addition to her duties as a Professor of Psychiatry and Obstetrics & Gynecology, Dr. Rasgon is also the Director of the Behavioral Neuroendocrinology Program and of the Women's Wellness Program.

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