School of Medicine
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Angelle Desiree LaBeaud
Associate Professor of Pediatrics (Infectious Diseases) and, by courtesy, of Health Research and Policy (Epidemiology) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests Arthropod-borne viruses are emerging and re-emerging infections that are spreading throughout the world. Our laboratory investigates the epidemiology of arboviral infections, focusing on the burden of disease and the long-term complications on human health. In particular, Dr. LaBeaud investigates dengue, chikungunya, and Rift Valley fever viruses in Kenya, where outbreaks cause fever, arthritis, retinitis, encephalitis, and hemorrhagic fever. Our main research questions focus on the risk factors for arboviral infections, the development of diagnostic tests that can be administered in the field to quickly determine what kind of arboviral infection a person has, and the genetic and immunologic investigation of why different people respond differently to the same infection. Our long-term goals are to contribute to a deeper understanding of arboviral infections and their long-term health consequences and to optimize control strategies to prevent these emerging infections. Our laboratory also investigates the effects of antenatal and postnatal parasitic infections on vaccine responses, growth, and development of Kenyan children.
My lab at Stanford supports the field work that is ongoing in Kenya, but we also have several projects that are based locally. We strive to improve diagnostics of arboviral infections and are using Luminex technology to build a new screening assay. We also have created a Luminex based platform to assess vaccine responses against multiple pathogens.
Norman J. Lacayo, MD
Associate Professor of Pediatrics (Hematology and Oncology) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests Pediatric Hematology/Oncology, Phase I drug studies for refractory and relapsed leukemia; genomic studies, biologic risk-stratification and treatment of acute myeloid leukemia; prediction or induction response and risk of relapse using phosphoproteomics in childhood AML; novel MRD techniques in childhood ALL.
Uri Ladabaum, MD
Professor of Medicine (Gastroenterology and Hepatology) at the Stanford University School of Medicine
Current Research and Scholarly Interests Gastrointestinal cancer prevention and risk management. Risk stratification. Cost-effectiveness analysis. Health services research.
Amy Ladd, MD
Professor of Orthopaedic Surgery (Hand Surgery) and, by courtesy, of Medicine (Immunology & Rheumatology) at the Stanford University Medical Center
Current Research and Scholarly Interests Research Interests
1. The kinematics and forces associated with thumb carpometcarpal (CMC) function and pathology
2. The anatomy, microstructure, and immunofluorescent characteristics of the thumb CMC joint
3. Pathomechaniics of CMC arthritis: biomechanical wear, injury, genetic, and environmental causes
4. Archiving, vitalizing, and innovating medical and surgical knowledge, most recently with innovative iBook monographs
Professor of Medicine (Nephrology) at the Stanford University Medical Center
Current Research and Scholarly Interests We are continuing to grow a glomerulonephritis cohort study, including immunologic characterization. We have completed interventional studies of preeclampsia exploring the nitric oxide, endothelin system and effects on glomerular function and morphometry. We continue to recruit patients for treatment and observational studies of glomerular disease, including FSGS, membranous and particularly IgA nephropathy. We also are actively studying renal disease in systemic amyloidosis.
Tze Leung Lai
Professor of Statistics and, by courtesy, of Biomedical Data Science
Current Research and Scholarly Interests Research interests include clinical trial design, cancer biostatistics, survival analysis, adaptation and sequential experimentation, change-point detection and segmentation, stochastic optimization, time series and inference on stochastic processes, hidden Markov models and genomic applications.