School of Medicine
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David M. Gaba, M.D.
Professor of Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests 1) Human Performance in Health Care, 2) Patient Safety in health care, 3) Simulation training in health care, 4) Organizational issues in safety in health care.
Instructor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests Our group studies how the human immune system responds to acute physiological perturbations, such as surgical trauma. Using high parameter single cell technologies (CyTOF) and proteomics approaches for the deep immune profiling of patients undergoing surgery, our research aims at identifying immune mechanisms (cell subsets and associated signaling pathways) that critically determine a patient's ability to heal and recover from surgical trauma.
Professor of Anesthesiology, Perioperative and Pain Medicine and, by courtesy, of Neurosurgery
Current Research and Scholarly Interests Astrocytes, microglia and neurons interact, and have unique vulnerabilities to injury based on their patterns of gene expression and their functional roles. We focus on the cellular and molecular basis of brain cell injury in stroke. We study the effects of altering miRNA expression, altering levels of heat shock and cell death regulatory proteins. Our goal is to improve outcome by improving mitochondrial function and brain cell survival, and reducing oxidative stress and inflammation.
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests My research interest is in improving systems practice, often harnessing techniques of medical simulation for training, development, testing, or implementation. Most recently, I have collaborated with Stanford and national colleagues on implementation of emergency manuals (context relevant sets of cognitive aids or checklists), for crisis management of critical events. See http://emergencymanual.stanford.edu and www.emergencymanuals.org with more details below.
Eric R. Gross
Assistant Professor of Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests Although opioids are addictive with many unwanted side effects, opioids prior to or during an ischemic event reduce cellular injury, unlike other analgesics such as COX-2 inhibitors which exacerbate injury. By studying how opioids reduce myocardial injury and how the pathways of nociception and cardioprotection are linked, we are designing next generation analgesics that are safe to use for those with cardiovascular disease.