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Dr. Bianxiao Cui is the Job and Gertrud Tamaki Professor of Chemistry and a fellow of the Wu Tsai Stanford Neuroscience Institute at Stanford University. She holds a Ph.D. degree in Chemistry from the University of Chicago and a BS degree from the University of Science and Technology of China. Dr. Cui develops new tools to study the nano-bio interface, electrophysiology, and signal transduction in cells at normal and disease conditions. As a scientist and a teacher, she enjoys working with young scientists to explore the natural world with scientific innovations. Research in her group spans the disciplines of physical chemistry, material science, nanotechnology, and neurobiology. Her awards and distinctions include Barany Award from Biophysical Society, NIH New Innovator Award, NSF CAREER award, NSF Inspire award, Packard Fellowships in Science and Engineering, Hellman Scholar, Searle Scholar Award and Dreyfus New Faculty Award.
Our objective is to develop new biophysical methods to advance current understandings of cellular machinery in the complicated environment of living cells. Creative applications of biophysical technologies such as crystallography, nuclear magnetic resonance and single-molecule fluorescence imaging have significantly advanced our understanding of biomolecular interactions and functions. However, traditional approaches that analyze purified biomolecules only yield insights that are removed from the cellular context. Our approach is to develop tools that precisely manipulate and measure biomolecular functions in live cells. Currently, we are focusing on four research areas: (1) Membrane curvature at the nano-bio interface; (2) Nanoelectrode arrays (NEAs) for scalable intracellular electrophysiology; (3) Electrochromic optical recording (ECORE) for neuroscience; and (4) Optical control of neurotrophin receptor tyrosine kinases. https://cuilab.stanford.edu/