Bio
Dr. Bernardo Bonilauri is a molecular biologist investigating the fundamental mechanisms of protein misfolding, cryptic peptides, and non-canonical codes in human biology and disease. He completed his postdoctoral training at the Stanford Cardiovascular Institute under the mentorship of Dr. Joseph C. Wu, after which he was appointed Instructor. In this role, he continues to develop advanced in vitro disease models to probe molecular and cellular processes underlying human pathology.
His research focuses on Transthyretin Amyloidosis (ATTR) and related protein misfolding disorders, applying multi-omics, structural biology, and stem cell–based platforms to dissect how pathogenic aggregates form and impair cellular function. In parallel, Dr. Bonilauri investigates microproteins encoded by small open reading frames (sORFs), with emphasis on their translation, subcellular localization, and biological functions in human cells.
By integrating molecular and cellular biology with systems-level analysis, his work seeks to reveal new biological mechanisms and identify therapeutic targets in understudied disease contexts.