Bio

Professional Education


  • PhD, Ludwig-Maximilians-University Munich, Germany, Biophysics (2012)
  • Diplom, Johannes Gutenberg Universitat Mainz (2007)
  • Vordiplom, Eberhard Karls Universitat Tubingen (2003)

Stanford Advisors


Publications

Journal Articles


  • Quantitative assessment of single-cell RNA-sequencing methods. Nature methods Wu, A. R., Neff, N. F., Kalisky, T., Dalerba, P., Treutlein, B., Rothenberg, M. E., Mburu, F. M., Mantalas, G. L., Sim, S., Clarke, M. F., Quake, S. R. 2014; 11 (1): 41-46

    Abstract

    Interest in single-cell whole-transcriptome analysis is growing rapidly, especially for profiling rare or heterogeneous populations of cells. We compared commercially available single-cell RNA amplification methods with both microliter and nanoliter volumes, using sequence from bulk total RNA and multiplexed quantitative PCR as benchmarks to systematically evaluate the sensitivity and accuracy of various single-cell RNA-seq approaches. We show that single-cell RNA-seq can be used to perform accurate quantitative transcriptome measurement in individual cells with a relatively small number of sequencing reads and that sequencing large numbers of single cells can recapitulate bulk transcriptome complexity.

    View details for DOI 10.1038/nmeth.2694

    View details for PubMedID 24141493

  • Single-Molecule Studies of RNA Polymerases CHEMICAL REVIEWS Michaelis, J., Treutlein, B. 2013; 113 (11): 8377-8399

    View details for DOI 10.1021/cr400207r

    View details for Web of Science ID 000327103200004

    View details for PubMedID 24053686

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